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yhiQ yhiQ prlC prlC yafS yafS yafE yafE smtA smtA yjjT yjjT ksgA ksgA kdtB kdtB yhiR yhiR rnpA rnpA ybaW ybaW
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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yhiQRibosomal RNA small subunit methyltransferase J; Specifically methylates the guanosine in position 1516 of 16S rRNA. (250 aa)    
Predicted Functional Partners:
prlC
Oligopeptidase A; Code: E; COG: COG0339.
  
  
 0.964
yafS
Conserved hypothetical protein; Code: QR; COG: COG0500.
 
  
 0.853
yafE
Putative biotin synthesis protein; Code: QR; COG: COG0500.
   
  
 0.827
smtA
S-adenosylmethionine-dependentmethyltransferase; Code: QR; COG: COG0500.
      
 0.808
yjjT
Putative enzyme; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
      
 0.738
ksgA
S-adenosylmethionine-6-N,N-adenosyl (rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.643
kdtB
Putative enzyme of lipopolysaccharide synthesis; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
  
 0.561
yhiR
Conserved hypothetical protein; Code: S; COG: COG2961.
       0.494
rnpA
RNase P, protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
    0.463
ybaW
Conserved hypothetical protein; Code: R; COG: COG0824.
 
     0.461
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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