node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
betA | betB | c0431 | c0432 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. Belongs to the GMC oxidoreductase family. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.998 |
betA | betI | c0431 | c0433 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. Belongs to the GMC oxidoreductase family. | Regulatory protein betI; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity). | 0.982 |
betA | betT | c0431 | c0434 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. Belongs to the GMC oxidoreductase family. | High-affinity choline transport protein; Escherichia coli K-12 ortholog: b0314; Escherichia coli O157:H7 ortholog: z0401; Belongs to the BCCT transporter (TC 2.A.15) family. | 0.971 |
betA | gltB | c0431 | c3973 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. Belongs to the GMC oxidoreductase family. | Glutamate synthase [NADPH] large chain precursor; Escherichia coli K-12 ortholog: b3212; Escherichia coli O157:H7 ortholog: z4576. | 0.676 |
betB | betA | c0432 | c0431 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. Belongs to the GMC oxidoreductase family. | 0.998 |
betB | betI | c0432 | c0433 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Regulatory protein betI; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity). | 0.990 |
betB | betT | c0432 | c0434 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | High-affinity choline transport protein; Escherichia coli K-12 ortholog: b0314; Escherichia coli O157:H7 ortholog: z0401; Belongs to the BCCT transporter (TC 2.A.15) family. | 0.949 |
betB | fmt | c0432 | c4048 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | 0.893 |
betB | folP | c0432 | c3933 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.564 |
betB | gltB | c0432 | c3973 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Glutamate synthase [NADPH] large chain precursor; Escherichia coli K-12 ortholog: b3212; Escherichia coli O157:H7 ortholog: z4576. | 0.420 |
betB | pckA | c0432 | c4176 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.679 |
betB | ppc | c0432 | c4915 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.589 |
betB | rpsL | c0432 | c4116 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.531 |
betB | ydbK | c0432 | c1823 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Probable pyruvate-flavodoxin oxidoreductase; Escherichia coli K-12 ortholog: b1378; Escherichia coli O157:H7 ortholog: z2332. | 0.706 |
betI | betA | c0433 | c0431 | Regulatory protein betI; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity). | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. Belongs to the GMC oxidoreductase family. | 0.982 |
betI | betB | c0433 | c0432 | Regulatory protein betI; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity). | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.990 |
betI | betT | c0433 | c0434 | Regulatory protein betI; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity). | High-affinity choline transport protein; Escherichia coli K-12 ortholog: b0314; Escherichia coli O157:H7 ortholog: z0401; Belongs to the BCCT transporter (TC 2.A.15) family. | 0.978 |
betT | betA | c0434 | c0431 | High-affinity choline transport protein; Escherichia coli K-12 ortholog: b0314; Escherichia coli O157:H7 ortholog: z0401; Belongs to the BCCT transporter (TC 2.A.15) family. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. Belongs to the GMC oxidoreductase family. | 0.971 |
betT | betB | c0434 | c0432 | High-affinity choline transport protein; Escherichia coli K-12 ortholog: b0314; Escherichia coli O157:H7 ortholog: z0401; Belongs to the BCCT transporter (TC 2.A.15) family. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.949 |
betT | betI | c0434 | c0433 | High-affinity choline transport protein; Escherichia coli K-12 ortholog: b0314; Escherichia coli O157:H7 ortholog: z0401; Belongs to the BCCT transporter (TC 2.A.15) family. | Regulatory protein betI; Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity). | 0.978 |