node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cvpA | purC | c2857 | c3004 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Escherichia coli K-12 ortholog: b2476; Escherichia coli O157:H7 ortholog: z3735. | 0.758 |
cvpA | purD | c2857 | c4963 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Phosphoribosylamine--glycine ligase; Escherichia coli K-12 ortholog: b4005; Escherichia coli O157:H7 ortholog: z5582; Belongs to the GARS family. | 0.516 |
cvpA | purE | c2857 | c0637 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.684 |
cvpA | purF | c2857 | c2856 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.989 |
cvpA | purH | c2857 | c4964 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Purine biosynthesis protein PurH; Bifunctional; Escherichia coli K-12 ortholog: b4006; Escherichia coli O157:H7 ortholog: z5583; bifunctional; Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | 0.645 |
cvpA | purK | c2857 | c0636 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.610 |
cvpA | purL | c2857 | c3080 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.950 |
cvpA | purM | c2857 | c3017 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Phosphoribosylformylglycinamidine cyclo-ligase; Escherichia coli K-12 ortholog: b2499; Escherichia coli O157:H7 ortholog: z3762; Belongs to the AIR synthase family. | 0.921 |
cvpA | purN | c2857 | c3018 | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.677 |
purB | purC | c1510 | c3004 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Escherichia coli K-12 ortholog: b2476; Escherichia coli O157:H7 ortholog: z3735. | 0.996 |
purB | purD | c1510 | c4963 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Phosphoribosylamine--glycine ligase; Escherichia coli K-12 ortholog: b4005; Escherichia coli O157:H7 ortholog: z5582; Belongs to the GARS family. | 0.959 |
purB | purE | c1510 | c0637 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.916 |
purB | purF | c1510 | c2856 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.976 |
purB | purH | c1510 | c4964 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Purine biosynthesis protein PurH; Bifunctional; Escherichia coli K-12 ortholog: b4006; Escherichia coli O157:H7 ortholog: z5583; bifunctional; Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | 0.997 |
purB | purK | c1510 | c0636 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.955 |
purB | purL | c1510 | c3080 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.990 |
purB | purM | c1510 | c3017 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Phosphoribosylformylglycinamidine cyclo-ligase; Escherichia coli K-12 ortholog: b2499; Escherichia coli O157:H7 ortholog: z3762; Belongs to the AIR synthase family. | 0.944 |
purB | purN | c1510 | c3018 | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.941 |
purC | cvpA | c3004 | c2857 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Escherichia coli K-12 ortholog: b2476; Escherichia coli O157:H7 ortholog: z3735. | Colicin V production protein; DedE protein; Escherichia coli K-12 ortholog: b2313; Escherichia coli O157:H7 ortholog: z3575. | 0.758 |
purC | purB | c3004 | c1510 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Escherichia coli K-12 ortholog: b2476; Escherichia coli O157:H7 ortholog: z3735. | Adenylosuccinate lyase; Escherichia coli K-12 ortholog: b1131; Escherichia coli O157:H7 ortholog: z1860. | 0.996 |