STRINGSTRING
xynZ xynZ Cthe_0912 Cthe_0912 cipA cipA celC celC Cthe_0661 Cthe_0661 Cthe_2548 Cthe_2548 xghA xghA Cthe_1904 Cthe_1904 celI celI celE celE Cthe_1838 Cthe_1838
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xynZGlycoside hydrolase family 10; KEGG: cce:Ccel_1232 carbohydrate binding family 6; PFAM: glycoside hydrolase family 10; Carbohydrate binding family 6; esterase; Dockerin type 1; SMART: glycoside hydrolase family 10; cellulose binding type IV. (837 aa)    
Predicted Functional Partners:
Cthe_0912
Glycoside hydrolase family 10; KEGG: cpy:Cphy_0624 endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; Carbohydrate-binding CenC domain protein; Dockerin type 1; esterase; SMART: glycoside hydrolase family 10.
 
 
 
0.896
cipA
Cellulosome anchoring protein cohesin region; Acts as a scaffolding protein in the cellulosome. It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes.
  
 
 
 0.880
celC
Glycoside hydrolase family 5; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
 
   
 0.828
Cthe_0661
Ricin B lectin; KEGG: scl:sce4015 hypothetical protein; PFAM: Ricin B lectin; glycoside hydrolase family 43; Dockerin type 1; SMART: Ricin B lectin; Belongs to the glycosyl hydrolase 43 family.
   
 0.820
Cthe_2548
alpha-L-arabinofuranosidase domain protein; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in small oligosaccharides as alpha-(1->5)-linked arabinobiose/arabinotriose, but does not display significant activity against linear non-substituted arabinan. It is also highly efficient in the cleavage of alpha-(1->3)- linked arabinoside of xylobiose and of the alpha-(1->3)-linked arabinoside decorations of polymeric wheat arabinoxylan. It exhibits very low act [...]
 
  
 0.728
xghA
Dockerin type 1; Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG. Has low activity on carboxymethylcellulose, lichenan,hydroxyethylcellulose and glucuronoxylan, and no activity on xylan, polygalaturonic acid, wheat arabinoxylan, rhamnogalacturan, curdlan, laminarin, galactomannan, galactan, arabinan and pachyman or amorphous cellulose (By similarity).
  
   
0.673
Cthe_1904
KEGG: hau:Haur_3129 amino acid adenylation domain-containing protein; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; major facilitator superfamily MFS_1; condensation domain protein; Thioesterase; phosphopantetheine-binding; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.668
celI
Glycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. Principally active against barley beta-glucan; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
 
  
 0.664
celE
Glycoside hydrolase family 5; Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan. Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) ; In the C-terminal section; belongs to the carbohydrate esterase 2 (CE2) family.
 
   
0.661
Cthe_1838
Glycoside hydrolase family 10; KEGG: cpy:Cphy_0624 endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; Carbohydrate-binding CenC domain protein; Dockerin type 1; SMART: glycoside hydrolase family 10.
 
 
 
0.655
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.