STRINGSTRING
cutC cutC cutD cutD Dde_1272 Dde_1272 Dde_3054 Dde_3054 Dde_3283 Dde_3283 Dde_3289 Dde_3289 Dde_3288 Dde_3288 Dde_3279 Dde_3279 Dde_3291 Dde_3291 Dde_3284 Dde_3284 Dde_0278 Dde_0278
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cutCFormate C-acetyltransferase; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Is involved in the anaerobic choline utilization pathway that allows D.alaskensis to grow on choline as a source of carbon and energy. Is strictly specific for choline as substrate. (846 aa)    
Predicted Functional Partners:
cutD
Glycyl-radical enzyme activating protein family; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via a homolytic cleavage of S-adenosyl-L-methionine (SAM). Is involved in the anaerobic choline utilization pathway that allows D.alaskensis to grow on choline as a source of carbon and energy; Belongs to the organic radical-activating enzymes family.
 
  
 0.970
Dde_1272
SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: Glycyl radical enzyme-activating; KEGG: dvl:Dvul_0490 glycyl-radical activating family protein; PFAM: Radical SAM; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
 
  
 0.915
Dde_3054
Glycyl-radical enzyme activating protein family; TIGRFAM: Glycyl radical enzyme-activating; KEGG: pth:PTH_2421 pyruvate-formate lyase-activating enzyme; PFAM: Radical SAM; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
 
  
 0.894
Dde_3283
KEGG: dsa:Desal_0467 acetaldehyde dehydrogenase-like protein.
 
  
 0.812
Dde_3289
KEGG: dsa:Desal_0464 hypothetical protein.
 
     0.723
Dde_3288
PFAM: Protein of unknown function DUF6, transmembrane; KEGG: dsa:Desal_0465 hypothetical protein.
  
     0.713
Dde_3279
KEGG: dsa:Desal_0471 acetaldehyde dehydrogenase (acetylating); TIGRFAM: Acetaldehyde dehydrogenase, acetylating.
 
  
 0.676
Dde_3291
KEGG: dsa:Desal_0463 MerR family transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR.
  
   
 0.649
Dde_3284
KEGG: dsa:Desal_0466 microcompartments protein; PFAM: Microcompartment protein, bacteria; SMART: Microcompartment protein, bacteria.
 
     0.592
Dde_0278
Anaerobic ribonucleoside-triphosphate reductase activating enzyme; PFAM: Radical SAM; KEGG: dvm:DvMF_1818 radical SAM domain protein.
  
  
 0.528
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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