STRINGSTRING
uppP uppP uppS uppS mecA mecA SAG0140 SAG0140 mraY mraY dgkA dgkA SAG0137 SAG0137 SAG1402 SAG1402 SAG0632 SAG0632 nth nth cpsA cpsA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
uppPUndecaprenol kinase, putative; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (279 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
    
 0.851
mecA
Negative regulator of competence MecA, putative; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
     
 0.823
SAG0140
Glycosyl transferase, group 4 family protein; Identified by match to PFAM protein family HMM PF00953.
    
 0.758
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.710
dgkA
Diacylglycerol kinase; Identified by match to PFAM protein family HMM PF01219.
    
 0.681
SAG0137
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.669
SAG1402
PAP2 family protein; Identified by match to PFAM protein family HMM PF01569.
  
 
 0.669
SAG0632
Psr protein; Identified by match to TIGR protein family HMM TIGR00350.
   
  
 0.627
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
   
 0.544
cpsA
Capsular polysaccharide biosynthesis protein CpsA; Identified by match to TIGR protein family HMM TIGR00350.
   
  
 0.529
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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