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cheR2 cheR2 aer2 aer2 cheB2 cheB2 cheD cheD PA0177 PA0177 PA0178 PA0178 cttP cttP aer aer pctB pctB pctC pctC PA4290 PA4290
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
cheR2Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (280 aa)    
Predicted Functional Partners:
aer2
Aerotaxis transducer Aer2; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 0.999
cheB2
Probable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
  
 0.997
cheD
Conserved hypothetical protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
  
 0.993
PA0177
Probable purine-binding chemotaxis protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.993
PA0178
Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.993
cttP
Chemotactic transducer for trichloroethylene [positive chemotaxis], CttP; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 0.987
aer
Aerotaxis receptor Aer; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 0.983
pctB
Chemotactic transducer PctB; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Responds to L-Arg, L-Gln, L-Ala, L-Glu, L-Lys, L-Met and L-Tyr. Also involved in repellent responses to trichloroethylene (TCE), chloroform and methylthiocyanate.
 
 0.969
pctC
Chemotactic transducer PctC; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Responds to L-His, L-Pro and GABA. Also involved in repellent responses to trichloroethylene (TCE), chloroform and methylthiocyanate.
 
 0.965
PA4290
Probable chemotaxis transducer; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 0.964
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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