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pvdL pvdL pvdD pvdD pvdJ pvdJ nuoD nuoD PA3327 PA3327 PA2412 PA2412 pvdG pvdG pvdE pvdE PA2402 PA2402 pvdA pvdA PA2411 PA2411
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pvdLPvdL; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (4342 aa)    
Predicted Functional Partners:
pvdD
Pyoverdine synthetase D; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
0.999
pvdJ
PvdJ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
0.999
nuoD
NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 0.998
PA3327
Probable non-ribosomal peptide synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
0.998
PA2412
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 
 0.997
pvdG
PvdG; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
  
 0.997
pvdE
Pyoverdine biosynthesis protein PvdE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 
 0.995
PA2402
Probable non-ribosomal peptide synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
0.993
pvdA
L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate.
 
 
 0.991
PA2411
Probable thioesterase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.990
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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