STRINGSTRING
exoS exoS pcrV pcrV popB popB popD popD exoY exoY exsC exsC exsD exsD pcrH pcrH exsA exsA PA3842 PA3842 pscF pscF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exoSExoenzyme S; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (453 aa)    
Predicted Functional Partners:
pcrV
Type III secretion protein PcrV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.983
popB
Translocator protein PopB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.983
popD
Translocator outer membrane protein PopD precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.983
exoY
Adenylate cyclase ExoY; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.959
exsC
ExsC, exoenzyme S synthesis protein C precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.957
exsD
ExsD; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.945
pcrH
Regulatory protein PcrH; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.941
exsA
Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.
   
  
 0.936
PA3842
Probable chaperone; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
    0.927
pscF
Type III export protein PscF; Major component of the type III secretion needle structure. Required for cytotoxicity on macrophages.
   
  
 0.925
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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