STRINGSTRING
fimX fimX wspR wspR fimW fimW pilZ pilZ rocS1 rocS1 chpA chpA gacS gacS fimL fimL PA4112 PA4112 PA3343 PA3343 PA0575 PA0575
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fimXFimX; Class 1: Function experimentally demonstrated in P. aeruginosa. (691 aa)    
Predicted Functional Partners:
wspR
Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 0.936
fimW
Hypothetical protein; High-affinity cyclic-di-GMP binding protein that regulates type IV pili (T4P) elongation. Required for T4P-mediated surface attachment and walking motility during the early phases of surface colonization. Not required for twitching motility. Does not bind related nucleotides such as GMP, GDP, GTP or ATP.
 
  
 0.929
pilZ
Type 4 fimbrial biogenesis protein PilZ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.914
rocS1
Probable two-component sensor; Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.898
chpA
Component of chemotactic signal transduction system; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.889
gacS
Sensor/response regulator hybrid; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  
 0.887
fimL
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.877
PA4112
Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.877
PA3343
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 
 0.874
PA0575
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 
0.873
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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