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PA5484 PA5484 algB algB PA0929 PA0929 pfeR pfeR PA3204 PA3204 gltR gltR pilH pilH aruR aruR PA5364 PA5364 creB creB parR parR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA5484Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (595 aa)    
Predicted Functional Partners:
algB
Two-component response regulator AlgB; Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. Positive regulator of the alginate biosynthetic gene AlgD.
 
 0.996
PA0929
Two-component response regulator; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 0.828
pfeR
Two-component response regulator PfeR; Member of the two-component regulatory system PfeR/PfeS. Activates expression of the ferric enterobactin receptor.
 
 0.827
PA3204
Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.782
gltR
Two-component response regulator GltR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 0.778
pilH
Twitching motility protein PilH; May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction).
 
 0.765
aruR
Probable two-component response regulator; Member of the two-component regulatory system AruS/AruR, which is involved in the regulation of the arginine transaminase (ATA) pathway in response to exogeneous L-arginine. Regulates transcription of aruH and aruI.
 
 0.750
PA5364
Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.743
creB
Two-component response regulator CreB; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 0.742
parR
Two-component response regulator, ParR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 0.734
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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