folE2-2 protein (Pseudomonas aeruginosa) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

folE2-2

Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (298 aa)

Predicted Functional Partners:

PA5540

0.993

PA5535

0.982

pyrQ

0.974

amiA

0.966

folE2

0.962

PA2666

0.954

folE1

0.954

PA5532

0.935

ribA

0.932

folX

0.923

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PA2666	folE1	PA2666	PA3438	Probable 6-pyruvoyl tetrahydrobiopterin synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.993
PA2666	folE2	PA2666	PA1674	Probable 6-pyruvoyl tetrahydrobiopterin synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.995
PA2666	folE2-2	PA2666	PA5539	Probable 6-pyruvoyl tetrahydrobiopterin synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	0.954
PA2666	folX	PA2666	PA3439	Probable 6-pyruvoyl tetrahydrobiopterin synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	D-erythro-7,8-dihydroneopterin triphosphate epimerase; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.	0.920
PA5532	PA5535	PA5532	PA5535	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.898
PA5532	PA5540	PA5532	PA5540	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.948
PA5532	amiA	PA5532	PA5538	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	N-acetylmuramoyl-L-alanine amidase; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.967
PA5532	folE2-2	PA5532	PA5539	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	0.935
PA5532	pyrQ	PA5532	PA5541	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Dihydroorotase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.570
PA5535	PA5532	PA5535	PA5532	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.898
PA5535	PA5540	PA5535	PA5540	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.979
PA5535	amiA	PA5535	PA5538	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	N-acetylmuramoyl-L-alanine amidase; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.954
PA5535	folE2-2	PA5535	PA5539	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	0.982
PA5535	pyrQ	PA5535	PA5541	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Dihydroorotase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.889
PA5540	PA5532	PA5540	PA5532	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.948
PA5540	PA5535	PA5540	PA5535	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.979
PA5540	amiA	PA5540	PA5538	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	N-acetylmuramoyl-L-alanine amidase; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.991
PA5540	folE2-2	PA5540	PA5539	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.	0.993
PA5540	pyrQ	PA5540	PA5541	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Dihydroorotase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.976
amiA	PA5532	PA5538	PA5532	N-acetylmuramoyl-L-alanine amidase; Product name confidence: Class 2 (High similarity to functionally studied protein).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.967