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glmS glmS nagB nagB glmM glmM SMU_435 SMU_435 glnA glnA gltA gltA glmU glmU pyrAB pyrAB pgi pgi purF purF manA manA
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second shell of interactors
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
glmSGlucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (604 aa)    
Predicted Functional Partners:
nagB
Putative N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.983
glmM
Putative phospho-sugar mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.976
SMU_435
Best Blastp Hit: gb|AAG21688.1| (AY007718) N-acetylglucosamine-6-phosphate deacetylase [Lactococcus lactis subsp. cremoris].
    
 0.972
glnA
Best Blastp Hit: gb|AAC44800.1| (U61271) glutamine synthetase type 1 [Streptococcus agalactiae].
 
 
 0.962
gltA
Best Blastp Hit: dbj|BAB05447.1| (AP001513) glutamate synthase (large subunit) [Bacillus halodurans].
  
 0.958
glmU
Putative UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
 0.939
pyrAB
Carbamoylphosphate synthetase, large subunit; Best Blastp Hit: emb|CAA03928.1| (AJ000109) carbamoylphosphate synthetase [Lactococcus lactis].
   
 0.936
pgi
Glucose-6-phosphate isomerase; Best Blastp Hit: gb|AAD33517.1|AF132127_2 (AF132127) glucose-6-phosphate isomerase [Streptococcus mutans].
  
 
 0.935
purF
Phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
0.921
manA
Best Blastp Hit: sp|Q59935|MANA_STRMU MANNOSE-6-PHOSPHATE ISOMERASE (PHOSPHOMANNOSE ISOMERASE) (PMI) (PHOSPHOHEXOMUTASE) >gi|451216|dbj|BAA04021.1| (D16594) Mannosephosphate Isomerase [Streptococcus mutans].
   
 
 0.916
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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