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YPO0099 YPO0099 YPO2252 YPO2252 hasF hasF ibeB ibeB YPO0617 YPO0617 macB1 macB1 macB2 macB2 irp1 irp1 YPO1944 YPO1944 YPO3343 YPO3343 irp2 irp2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YPO0099Putative exported protein; Similar to several members of the HlyD family of secretion proteins e.g. Escherichia coli colicin V secretion protein CvaA SW:CVAA_ECOLI (P22519) (413 aa) fasta scores: E(): 0, 47.1% id in 410 aa and to Escherichia coli MtfA TR:Q46972 (EMBL:U47048) (414 aa) fasta scores: E(): 0, 46.6% id in 410 aa. (411 aa)    
Predicted Functional Partners:
YPO2252
Putative toxin transport protein (pseudogene); PS00543 HlyD family secretion proteins signature.
 
 0.940
hasF
Similar to Serratia marcescens haemophore (HasA) ABC-transporter outer membrane component, HasF TR:Q54452 (EMBL:X98513) (500 aa) fasta scores: E(): 0, 76.7% id in 455 aa, and to Escherichia coli ABC-transporter outer membrane protein, TolC SW:TOLC_ECOLI (P02930) (495 aa) fasta scores: E(): 0, 73.2% id in 470 aa.
 
 0.902
ibeB
Similar to Escherichia coli probable outer membrane lipoprotein IbeB precursor SW:IBEB_ECOLI (P77211) (457 aa) fasta scores: E(): 0, 38.8% id in 464 aa, and to Pseudomonas aeruginosa outer membrane protein OprM precursor or OprK or Pa0427 TR:AAG03816 (EMBL:L23839) (485 aa) fasta scores: E(): 0, 48.0% id in 469 aa.
  
 0.843
YPO0617
Putative membrane protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
  
 0.842
macB1
Putative ABC transporter ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.817
macB2
Putative ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.817
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
 
  
 0.696
YPO1944
Putative membrane protein; Previously sequenced as Yersinia pestis hypothetical protein TR:Q9ZC54 (EMBL:AL031866) (430 aa) fasta scores: E(): 0, 100.0% id in 430 aa. Similar to Campylobacter jejuni possible ABC transport system permease protein Cj1661 TR:Q9PM16 (EMBL:AL139079) (430 aa) fasta scores: E(): 0, 36.1% id in 435 aa.
 
  
 0.625
YPO3343
Probable extracellular solute-binding protein; Similar to Pseudomonas aeruginosa cyclohexadienyl dehydratase precursor [includes: prephenate dehydratase and arogenate dehydratase] PheC or Pa3475 SW:PHEC_PSEAE (Q01269) (268 aa) fasta scores: E(): 7.6e-27, 37.1% id in 251 aa, and to Vibrio cholerae amino acid ABC transporter,periplasmic amino acid-binding protein Vca1039 TR:Q9KKR3 (EMBL:AE004429) (278 aa) fasta scores: E(): 6.5e-14, 25.7% id in 245 aa.
  
     0.522
irp2
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 100.0% id in 2035 aa. Similar to Yersinia enterocolitica high-molecular-weight protein 2 Irp2 SW:HMP2_YEREN (P48633) (2035 aa) fasta scores: E(): 0, 98.6% id in 2035 aa. The previously sequenced Yersinia pestis Irp2 ORF starts at a valine situated 6 aa upstream from the methionine. However,the methionine start, has a good ribosome-binding site.
  
    0.520
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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