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nagK nagK nagE nagE nagA nagA glcA glcA treB treB nanE nanE murQ murQ ycfO ycfO lolE lolE mlc mlc nagC nagC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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Score
nagKConserved hypothetical protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. Belongs to the ROK (NagC/XylR) family. NagK subfamily. (256 aa)    
Predicted Functional Partners:
nagE
Similar to Escherichia coli PTS system,N-acetylglucosamine-specific IIABC component NagE SW:PTAA_ECOLI (P09323) (648 aa) fasta scores: E(): 0, 52.6% id in 683 aa, and to Vibrio furnissii PTS permease for N-acetylglucosamine and glucose NagE TR:P96161 (EMBL:U65014) (496 aa) fasta scores: E(): 0, 69.9% id in 495 aa.
  
 0.996
nagA
Similar to Escherichia coli N-acetylglucosamine-6-phosphate deacetylase NagA SW:NAGA_ECOLI (P15300) (382 aa) fasta scores: E(): 0, 75.1% id in 381 aa, and to Vibrio cholerae N-acetylglucosamine-6-phosphate deacetylase NagA SW:NAGA_VIBCH (O32445) (378 aa) fasta scores: E(): 0, 64.1% id in 376 aa.
 
 
 0.972
glcA
Similar to Escherichia coli PTS system,glucose-specific IIBC component Ptsg or Glca or UmG SW:PTGB_ECOLI (P05053) (477 aa) fasta scores: E(): 0, 90.4% id in 477 aa, and to Salmonella typhimurium PTS system,glucose-specific IIBC component PtsG SW:PTGB_SALTY (P37439) (477 aa) fasta scores: E(): 0, 88.7% id in 477 aa.
  
 0.958
treB
Similar to Escherichia coli PTS system,trehalose-specific IIBC component TreB SW:PTTB_ECOLI (P36672) (473 aa) fasta scores: E(): 0, 80.5% id in 471 aa,and to Vibrio cholerae PTS system, trehalose-specific IIBC component Vc0910 TR:Q9KTJ2 (EMBL:AE004175) (478 aa) fasta scores: E(): 0, 70.0% id in 474 aa.
  
 0.958
nanE
Putative outer membrane protein (pseudogene); Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
  
 
 0.944
murQ
Putative glucokinase protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
     
 0.943
ycfO
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
    
  0.932
lolE
Similar to Escherichia coli lipoprotein releasing system transmembrane protein LolE SW:LOLE_ECOLI (P75958) (413 aa) fasta scores: E(): 0, 79.6% id in 411 aa.
 
    0.893
mlc
LysR-family transcriptional regulatory protein (pseudogene); Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family, score 49.10, E-value 2.4e-11.
 
    0.777
nagC
Putative N-acetylglucosamine regulatory protein; Similar to Escherichia coli N-acetylglucosamine repressor NagC or NagR or B0676 SW:NAGC_ECOLI (P15301) (406 aa) fasta scores: E(): 0, 78.0% id in 405 aa, and to Vibrio cholerae probable N-acetylglucosamine regulatory protein VC0993 TR:Q9KTB0 (EMBL:AE004181) (404 aa) fasta scores: E(): 0, 63.3% id in 403 aa.
  
    0.775
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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