node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apk | asd-2 | YPO3719 | YPO3949 | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.991 |
apk | aspB | YPO3719 | YPO3557 | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 87.4% id in 1497 aa, and to Vibrio cholerae glutamate synthase, large subunit Vc2376 TR:Q9KPJ1 (EMBL:AE004308) (1487 aa) fasta scores: E(): 0, 73.7% id in 1488 aa. | 0.524 |
apk | dapA | YPO3719 | YPO3062 | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.786 |
apk | dapF | YPO3719 | YPO3845 | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.614 |
apk | metL | YPO3719 | YPO0116 | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | Cystathionine gamma-synthase (pseudogene); PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.980 |
apk | thrA | YPO3719 | YPO0459 | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I ThrA SW:AK1H_ECOLI (P00561) (820 aa) fasta scores: E(): 0, 82.0% id in 821 aa,and to Serratia marcescens bifunctional aspartokinase/homoserine dehydrogenase I ThrA SW:AK1H_SERMA (P27725) (819 aa) fasta scores: E(): 0, 89.9% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.980 |
apk | thrB | YPO3719 | YPO0460 | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.945 |
apk | thrC | YPO3719 | YPO0461 | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | Threonine synthase; Similar to Escherichia coli threonine synthase ThrC SW:THRC_ECOLI (P00934) (428 aa) fasta scores: E(): 0, 83.1% id in 425 aa, and to Serratia marcescens threonine synthase ThrC SW:THRC_SERMA (P27735) (429 aa) fasta scores: E(): 0,89.3% id in 428 aa. | 0.917 |
asd-2 | apk | YPO3949 | YPO3719 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | 0.991 |
asd-2 | aspB | YPO3949 | YPO3557 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 87.4% id in 1497 aa, and to Vibrio cholerae glutamate synthase, large subunit Vc2376 TR:Q9KPJ1 (EMBL:AE004308) (1487 aa) fasta scores: E(): 0, 73.7% id in 1488 aa. | 0.741 |
asd-2 | dapA | YPO3949 | YPO3062 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.986 |
asd-2 | dapF | YPO3949 | YPO3845 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.784 |
asd-2 | metL | YPO3949 | YPO0116 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Cystathionine gamma-synthase (pseudogene); PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.998 |
asd-2 | nifJ | YPO3949 | YPO2334 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa. | 0.702 |
asd-2 | pgk | YPO3949 | YPO0921 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Similar to Escherichia coli phosphoglycerate kinase Pgk SW:PGK_ECOLI (P11665) (386 aa) fasta scores: E(): 0,88.6% id in 386 aa, and to Haemophilus influenzae phosphoglycerate kinase Pgk SW:PGK_HAEIN (P43726) (385 aa) fasta scores: E(): 0, 79.2% id in 385 aa. | 0.818 |
asd-2 | thrA | YPO3949 | YPO0459 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I ThrA SW:AK1H_ECOLI (P00561) (820 aa) fasta scores: E(): 0, 82.0% id in 821 aa,and to Serratia marcescens bifunctional aspartokinase/homoserine dehydrogenase I ThrA SW:AK1H_SERMA (P27725) (819 aa) fasta scores: E(): 0, 89.9% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.998 |
asd-2 | thrB | YPO3949 | YPO0460 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.725 |
asd-2 | thrC | YPO3949 | YPO0461 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Threonine synthase; Similar to Escherichia coli threonine synthase ThrC SW:THRC_ECOLI (P00934) (428 aa) fasta scores: E(): 0, 83.1% id in 425 aa, and to Serratia marcescens threonine synthase ThrC SW:THRC_SERMA (P27735) (429 aa) fasta scores: E(): 0,89.3% id in 428 aa. | 0.738 |
aspB | apk | YPO3557 | YPO3719 | Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 87.4% id in 1497 aa, and to Vibrio cholerae glutamate synthase, large subunit Vc2376 TR:Q9KPJ1 (EMBL:AE004308) (1487 aa) fasta scores: E(): 0, 73.7% id in 1488 aa. | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 81.5% id in 448 aa, and to Vibrio cholerae aspartokinase III, lysine-sensitive Vc0391 TR:Q9KUW8 (EMBL:AE004127) (479 aa) fasta scores: E(): 0,55.2% id in 453 aa; Belongs to the aspartokinase family. | 0.524 |
aspB | asd-2 | YPO3557 | YPO3949 | Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 87.4% id in 1497 aa, and to Vibrio cholerae glutamate synthase, large subunit Vc2376 TR:Q9KPJ1 (EMBL:AE004308) (1487 aa) fasta scores: E(): 0, 73.7% id in 1488 aa. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.741 |