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sahH sahH metH metH metE metE metZ metZ metB metB cbs cbs mtn mtn metC metC MMAR_3921 MMAR_3921 MMAR_3453 MMAR_3453 thrA thrA
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sahHAdenosylhomocysteinase SahH; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (492 aa)    
Predicted Functional Partners:
metH
5-methyltetrahydrofolate--homocysteine methyltransferase, MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.968
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase MetE; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.960
metZ
O-succinylhomoserine sulfhydrylase, MetZ; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.947
metB
Cystathionine gamma-synthase MetB (cgs); Involved in methionine biosynthesis: converts O- succinyl-L-homoserine to cystathionine [catalytic activity : O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate (can also use hydrogen sulfide and methanethiol as substrates)].
  
 0.938
cbs
Cystathionine beta-synthase Cbs; Thought to be involved in homocysteine transulfuration [catalytic activity: L-serine + L- homocysteine = cystathionine + H2O].
  
 0.938
mtn
Bifunctional Mta/Sah nucleosidase Mtn; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
 0.918
metC
O-acetylhomoserine sulfhydrylase MetC; Transforms O-acetylhomoserine into L-methionine [catalytic activity: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate].
    
 0.916
MMAR_3921
Conserved hypothetical phage DNA methylase; Function unknown; possible role in phage DNA restriction modification system.
    
 0.911
MMAR_3453
Aminotransferase.
     
  0.900
thrA
Homoserine dehydrogenase ThrA; Involved in the conversion of l-aspartate to homoserine (third step). homoserine participates in the biosynthesis of threonine and then isoleucine and in the biosynthesis of methionine [catalytic activity : L- homoserine + NAD(P)(+) = l-aspartate 4-semialdehyde + NAD(P)H.].
 
 
 0.865
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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