node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMAR_1135 | MMAR_1718 | MMAR_1135 | MMAR_1718 | Conserved hypothetical protein. | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | 0.457 |
MMAR_1135 | MMAR_3629 | MMAR_1135 | MMAR_3629 | Conserved hypothetical protein. | Conserved hypothetical membrane protein. | 0.451 |
MMAR_1496 | MMAR_1718 | MMAR_1496 | MMAR_1718 | Oxidoreductase. | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | 0.634 |
MMAR_1717 | MMAR_1718 | MMAR_1717 | MMAR_1718 | Conserved integral membrane transport protein; Function unknown; contains major facilitator superfamily (MFS). the MFS transporters are single- polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | 0.741 |
MMAR_1717 | gltS | MMAR_1717 | MMAR_1719 | Conserved integral membrane transport protein; Function unknown; contains major facilitator superfamily (MFS). the MFS transporters are single- polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. | glutamyl-tRNA synthetase GltS; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.718 |
MMAR_1718 | MMAR_1135 | MMAR_1718 | MMAR_1135 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | Conserved hypothetical protein. | 0.457 |
MMAR_1718 | MMAR_1496 | MMAR_1718 | MMAR_1496 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | Oxidoreductase. | 0.634 |
MMAR_1718 | MMAR_1717 | MMAR_1718 | MMAR_1717 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | Conserved integral membrane transport protein; Function unknown; contains major facilitator superfamily (MFS). the MFS transporters are single- polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. | 0.741 |
MMAR_1718 | MMAR_2730 | MMAR_1718 | MMAR_2730 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | Oxidoreductase; Function unknown, probably involved in cellular metabolism. | 0.433 |
MMAR_1718 | MMAR_2865 | MMAR_1718 | MMAR_2865 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | Oxygenase; Function unknown, may be involved in electron transfer. | 0.418 |
MMAR_1718 | MMAR_3629 | MMAR_1718 | MMAR_3629 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | Conserved hypothetical membrane protein. | 0.451 |
MMAR_1718 | MMAR_4110 | MMAR_1718 | MMAR_4110 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | This family of dehydrogenases act on aldehyde substrates. members use NADP as a cofactor; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.488 |
MMAR_1718 | argH | MMAR_1718 | MMAR_2469 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | Argininosuccinate lyase ArgH; Arginine biosynthesis (last step) [catalytic activity : n-(L-arginino)succinate = fumarate + l- arginine]. | 0.509 |
MMAR_1718 | ggtA | MMAR_1718 | MMAR_4920 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | Bifunctional acylase, GgtA; Besides the cephalosporin acylase I activity which converts GL-7ACA into 7-Aca; this enzyme displays some gamma glutamyltranspeptidase activity: Ggt plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione. [catalytic activity 1: 7-beta-(4-carboxybutanamido)-cephalosporanic acid + H2O = 7-aminocephalosporanic acid + glutaric acid] [catalytic activity 2: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid]. | 0.436 |
MMAR_1718 | gltS | MMAR_1718 | MMAR_1719 | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | glutamyl-tRNA synthetase GltS; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.904 |
MMAR_2730 | MMAR_1718 | MMAR_2730 | MMAR_1718 | Oxidoreductase; Function unknown, probably involved in cellular metabolism. | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | 0.433 |
MMAR_2730 | MMAR_2865 | MMAR_2730 | MMAR_2865 | Oxidoreductase; Function unknown, probably involved in cellular metabolism. | Oxygenase; Function unknown, may be involved in electron transfer. | 0.430 |
MMAR_2865 | MMAR_1718 | MMAR_2865 | MMAR_1718 | Oxygenase; Function unknown, may be involved in electron transfer. | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Isomerizes HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) to ohed (2-OXO-hept-3-ene-1,7-dioate). | 0.418 |
MMAR_2865 | MMAR_2730 | MMAR_2865 | MMAR_2730 | Oxygenase; Function unknown, may be involved in electron transfer. | Oxidoreductase; Function unknown, probably involved in cellular metabolism. | 0.430 |
MMAR_2865 | MMAR_4110 | MMAR_2865 | MMAR_4110 | Oxygenase; Function unknown, may be involved in electron transfer. | This family of dehydrogenases act on aldehyde substrates. members use NADP as a cofactor; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.587 |