node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMAR_1780 | MMAR_1781 | MMAR_1780 | MMAR_1781 | Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning. | Conserved hypothetical protein. | 0.951 |
MMAR_1780 | MMAR_1784 | MMAR_1780 | MMAR_1784 | Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning. | Conserved protein; Function unknown. contains N-term OsmC-like protein domain and C-term AcyP, acylphosphatases domain. | 0.752 |
MMAR_1780 | fpg | MMAR_1780 | MMAR_1783 | Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning. | formamidopyrimidine-DNA glycosylase Fpg; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.796 |
MMAR_1780 | polA | MMAR_1780 | MMAR_2432 | Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.429 |
MMAR_1780 | rnc | MMAR_1780 | MMAR_1782 | Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning. | Ribonuclease III Rnc; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.907 |
MMAR_1781 | MMAR_1780 | MMAR_1781 | MMAR_1780 | Conserved hypothetical protein. | Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning. | 0.951 |
MMAR_1781 | MMAR_1784 | MMAR_1781 | MMAR_1784 | Conserved hypothetical protein. | Conserved protein; Function unknown. contains N-term OsmC-like protein domain and C-term AcyP, acylphosphatases domain. | 0.767 |
MMAR_1781 | fpg | MMAR_1781 | MMAR_1783 | Conserved hypothetical protein. | formamidopyrimidine-DNA glycosylase Fpg; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.907 |
MMAR_1781 | rnc | MMAR_1781 | MMAR_1782 | Conserved hypothetical protein. | Ribonuclease III Rnc; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.966 |
MMAR_1784 | MMAR_1780 | MMAR_1784 | MMAR_1780 | Conserved protein; Function unknown. contains N-term OsmC-like protein domain and C-term AcyP, acylphosphatases domain. | Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning. | 0.752 |
MMAR_1784 | MMAR_1781 | MMAR_1784 | MMAR_1781 | Conserved protein; Function unknown. contains N-term OsmC-like protein domain and C-term AcyP, acylphosphatases domain. | Conserved hypothetical protein. | 0.767 |
MMAR_1784 | fpg | MMAR_1784 | MMAR_1783 | Conserved protein; Function unknown. contains N-term OsmC-like protein domain and C-term AcyP, acylphosphatases domain. | formamidopyrimidine-DNA glycosylase Fpg; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.778 |
MMAR_1784 | rnc | MMAR_1784 | MMAR_1782 | Conserved protein; Function unknown. contains N-term OsmC-like protein domain and C-term AcyP, acylphosphatases domain. | Ribonuclease III Rnc; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.767 |
MMAR_4559 | fpg | MMAR_4559 | MMAR_1783 | formamidopyrimidine-DNA glycosylase; This enzyme may play a significant role in processes leading to recovery from mutagenesis and/or cell death by alkylating agents [catalytic activity: hydrolysis of DNA containing ring-opened N7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N- methyl)formamidopyrimide]; Belongs to the FPG family. | formamidopyrimidine-DNA glycosylase Fpg; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.932 |
MMAR_4559 | mutY | MMAR_4559 | MMAR_5089 | formamidopyrimidine-DNA glycosylase; This enzyme may play a significant role in processes leading to recovery from mutagenesis and/or cell death by alkylating agents [catalytic activity: hydrolysis of DNA containing ring-opened N7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N- methyl)formamidopyrimide]; Belongs to the FPG family. | Adenine glycosylase MutY; Involved in base excision repair. removes adenine mispaired with 8-OXOG. may repair a.G and a.C mismatches by adenine excision. | 0.635 |
MMAR_4559 | nth | MMAR_4559 | MMAR_5162 | formamidopyrimidine-DNA glycosylase; This enzyme may play a significant role in processes leading to recovery from mutagenesis and/or cell death by alkylating agents [catalytic activity: hydrolysis of DNA containing ring-opened N7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N- methyl)formamidopyrimide]; Belongs to the FPG family. | Endonuclease III Nth; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.437 |
MMAR_4559 | polA | MMAR_4559 | MMAR_2432 | formamidopyrimidine-DNA glycosylase; This enzyme may play a significant role in processes leading to recovery from mutagenesis and/or cell death by alkylating agents [catalytic activity: hydrolysis of DNA containing ring-opened N7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N- methyl)formamidopyrimide]; Belongs to the FPG family. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.848 |
fpg | MMAR_1780 | MMAR_1783 | MMAR_1780 | formamidopyrimidine-DNA glycosylase Fpg; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Conserved protein; Function unknown, possibly involved in cell division and chromosome partitioning. | 0.796 |
fpg | MMAR_1781 | MMAR_1783 | MMAR_1781 | formamidopyrimidine-DNA glycosylase Fpg; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Conserved hypothetical protein. | 0.907 |
fpg | MMAR_1784 | MMAR_1783 | MMAR_1784 | formamidopyrimidine-DNA glycosylase Fpg; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Conserved protein; Function unknown. contains N-term OsmC-like protein domain and C-term AcyP, acylphosphatases domain. | 0.778 |