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rnhB rnhB lepB lepB coaE coaE MMAR_3304 MMAR_3304 rplS rplS dnaN_1 dnaN_1 polA polA dnaN dnaN MMAR_1180 MMAR_1180 MMAR_3099 MMAR_3099 lppK lppK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rnhBRibonuclease HII protein RnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (239 aa)    
Predicted Functional Partners:
lepB
Signal peptidase I LepB; Cleavage of N-terminal leader sequences from secreted protein precursors; Belongs to the peptidase S26 family.
  
  
 0.966
coaE
dephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.913
MMAR_3304
Conserved hypothetical protein.
  
 
 0.900
rplS
50S ribosomal protein L19 RplS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
   
 0.837
dnaN_1
Probably involved in phage genome replication. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. this DNA polymerase also exhibits 3' to 5' exonuclease activity. the beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA [catalytic activity: N deoxynucleoside triphosphate = N diphosphate + {DNA}n].
 
 
 0.803
polA
DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 0.790
dnaN
DNA polymerase III (beta chain) DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
 
 
 0.788
MMAR_1180
N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide.
  
 
 0.765
MMAR_3099
Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP).
  
 
 0.765
lppK
Conserved lipoprotein, LppK.
  
 
 0.760
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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