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pyrD pyrD pyrC pyrC pyrE pyrE pheT pheT pyrB pyrB carB carB MMAR_3409 MMAR_3409 pyrF pyrF carA carA MMAR_2865 MMAR_2865 MMAR_0644 MMAR_0644
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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pyrDDihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (360 aa)    
Predicted Functional Partners:
pyrC
Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.991
pyrE
Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.986
pheT
phenylalanyl-tRNA synthetase, beta chain PheT; Charging phe-tRNA [catalytic activity : ATP + L- phenylalanine + tRNA(Phe) = AMP + diphosphate + L- phenylalanyl-tRNA(Phe)]; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.934
pyrB
Aspartate carbamoyltransferase PyrB; Involved in pyrimidine biosynthesis (second step) [catalytic activity : carbamoyl phosphate + l-aspartate = phosphate + N-carbamoyl-L-aspartate]; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.926
carB
Carbamoyl-phosphate synthase large chain CarB; Involved in both arginine and pyrimidine biosynthesis [catalytic activity : 2 ATP + L-glutamine + CO(2) + H(2)O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.]; Belongs to the CarB family.
 
 
 0.915
MMAR_3409
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.
     
  0.900
pyrF
Orotidine 5'-phosphate decarboxylase PyrF; Involved in the biosynthesis of pyrimidines [catalytic activity : orotidine 5'-phosphate = ump + CO(2)]; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.895
carA
Carbamoyl-phosphate synthase small chain CarA; Involved in both arginine and pyrimidine biosynthesis [catalytic activity : 2 ATP + L-glutamine + CO(2) + H(2)O = 2 ADP + phosphate + glutamate + carbamoyl phosphate]; Belongs to the CarA family.
 
  
 0.878
MMAR_2865
Oxygenase; Function unknown, may be involved in electron transfer.
  
 
 0.866
MMAR_0644
Monooxygenase; Function unknown, probably involved in cellular metabolism; Belongs to the globin family.
  
 
 0.849
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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