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fum fum sdhA sdhA mdh mdh mqo mqo glcB glcB sdhA_1 sdhA_1 sdhB sdhB sdhC sdhC mez_1 mez_1 sdhB_1 sdhB_1 gltA2 gltA2
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query proteins and first shell of interactors
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second shell of interactors
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
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protein homology
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fumFumarase Fum; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (476 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase (flavoprotein subunit) SdhA; Involved in tricarboxylic acid cycle. membrane- bound FAD-containing enzyme which is responsible for succinate interconversion [catalytic activity: succinate + acceptor = fumarate + reduced acceptor].
 0.991
mdh
Malate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.986
mqo
Malate:quinone oxidoreductase Mqo; Involved in tricarboxylic acid cycle [catalytic activity: (S)-malate + acceptor = oxaloacetate + reduced acceptor].
    
 0.977
glcB
Malate synthase G GlcB; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.976
sdhA_1
Succinate dehydrogenase (iron-sulfur subunit), SdhA_1; Involved in interconversion of fumarate and succinate (aerobic respiration) [catalytic activity: succinate + acceptor = fumarate + reduced acceptor].
 0.970
sdhB
Succinate dehydrogenase (iron-sulphur protein subunit) SdhB; Involved in tricarboxylic acid cycle. membrane- bound FAD-containing enzyme which is responsible for succinate interconversion [catalytic activity: succinate + acceptor = fumarate + reduced acceptor].
 
 0.960
sdhC
Succinate dehydrogenase (cytochrome B-556 subunit) SdhC; Involved in tricarboxylic acid cycle. mono-heme cytochrome of the succinate dehydrogenase complex.
  
 
 0.959
mez_1
[NAD] dependent malate oxidoreductase Mez_1; Catalizes the oxidative decarboxylation of malate into pyruvate, important for a wide range of metabolic pathways [catalytic activity: (S)-malate + NAD(+) = pyruvate + CO(2) + NADH].
 
 
 0.957
sdhB_1
Succinate dehydrogenase (iron-sulfur subunit), SdhB_1; Involved in interconversion of fumarate and succinate (aerobic respiration) [catalytic activity: succinate + acceptor = fumarate + reduced acceptor].
  
 0.954
gltA2
Citrate synthase I GltA2; Involved in tricarboxylic acid cycle (krebs cycle) [catalytic activity: citrate + CoA = acetyl-CoA + H2O + oxaloacetate]; Belongs to the citrate synthase family.
  
 0.951
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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