node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO53684.1 | cobA | PSPTO_0130 | PSPTO_2300 | uroporphyrin-III C-methyltransferase, putative; See PMID:20190049 for expression data. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.903 |
AAO53684.1 | cobI | PSPTO_0130 | PSPTO_4875 | uroporphyrin-III C-methyltransferase, putative; See PMID:20190049 for expression data. | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.900 |
AAO53684.1 | cysG | PSPTO_0130 | PSPTO_3344 | uroporphyrin-III C-methyltransferase, putative; See PMID:20190049 for expression data. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.910 |
AAO53684.1 | hemC | PSPTO_0130 | PSPTO_0128 | uroporphyrin-III C-methyltransferase, putative; See PMID:20190049 for expression data. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.791 |
AAO53684.1 | hemD | PSPTO_0130 | PSPTO_0129 | uroporphyrin-III C-methyltransferase, putative; See PMID:20190049 for expression data. | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.991 |
AAO53684.1 | hemE | PSPTO_0130 | PSPTO_5118 | uroporphyrin-III C-methyltransferase, putative; See PMID:20190049 for expression data. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.908 |
AAO58306.1 | cobA | PSPTO_4877 | PSPTO_2300 | Cobalamin biosynthesis protein CobG, putative; See PMID:20190049 for expression data. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.717 |
AAO58306.1 | cobI | PSPTO_4877 | PSPTO_4875 | Cobalamin biosynthesis protein CobG, putative; See PMID:20190049 for expression data. | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.986 |
AAO58306.1 | cysG | PSPTO_4877 | PSPTO_3344 | Cobalamin biosynthesis protein CobG, putative; See PMID:20190049 for expression data. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.906 |
AAO58306.1 | cysH | PSPTO_4877 | PSPTO_2280 | Cobalamin biosynthesis protein CobG, putative; See PMID:20190049 for expression data. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.867 |
AAO58306.1 | cysN/C | PSPTO_4877 | PSPTO_4432 | Cobalamin biosynthesis protein CobG, putative; See PMID:20190049 for expression data. | Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.962 |
cobA | AAO53684.1 | PSPTO_2300 | PSPTO_0130 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrin-III C-methyltransferase, putative; See PMID:20190049 for expression data. | 0.903 |
cobA | AAO58306.1 | PSPTO_2300 | PSPTO_4877 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CobG, putative; See PMID:20190049 for expression data. | 0.717 |
cobA | cobI | PSPTO_2300 | PSPTO_4875 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.934 |
cobA | cysG | PSPTO_2300 | PSPTO_3344 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.960 |
cobA | cysH | PSPTO_2300 | PSPTO_2280 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.718 |
cobA | cysI | PSPTO_2300 | PSPTO_2730 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Sulphite reductase; See PMID:20190049 for expression data. | 0.804 |
cobA | cysN/C | PSPTO_2300 | PSPTO_4432 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.766 |
cobA | hemC | PSPTO_2300 | PSPTO_0128 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.986 |
cobA | hemD | PSPTO_2300 | PSPTO_0129 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthetase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.925 |