node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
atpB | qcrA | BSU36870 | BSU22560 | ATP synthase (subunit a, component F0); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | Menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit); Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. | 0.561 |
atpB | resA | BSU36870 | BSU23150 | ATP synthase (subunit a, component F0); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | 0.622 |
atpB | resB | BSU36870 | BSU23140 | ATP synthase (subunit a, component F0); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.741 |
atpB | resC | BSU36870 | BSU23130 | ATP synthase (subunit a, component F0); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.689 |
bdbD | ccdA | BSU33480 | BSU17930 | Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation. | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | 0.933 |
bdbD | resA | BSU33480 | BSU23150 | Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation. | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | 0.921 |
bdbD | resB | BSU33480 | BSU23140 | Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.467 |
bdbD | resC | BSU33480 | BSU23130 | Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.603 |
cccA | qcrA | BSU25190 | BSU22560 | Cytochrome c550; Not essential for growth on minimal or rich media. | Menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit); Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. | 0.986 |
cccA | resA | BSU25190 | BSU23150 | Cytochrome c550; Not essential for growth on minimal or rich media. | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | 0.771 |
cccA | resB | BSU25190 | BSU23140 | Cytochrome c550; Not essential for growth on minimal or rich media. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.816 |
cccA | resC | BSU25190 | BSU23130 | Cytochrome c550; Not essential for growth on minimal or rich media. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.785 |
ccdA | bdbD | BSU17930 | BSU33480 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation. | 0.933 |
ccdA | resA | BSU17930 | BSU23150 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | 0.994 |
ccdA | resB | BSU17930 | BSU23140 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.995 |
ccdA | resC | BSU17930 | BSU23130 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.991 |
qcrA | atpB | BSU22560 | BSU36870 | Menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit); Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. | ATP synthase (subunit a, component F0); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | 0.561 |
qcrA | cccA | BSU22560 | BSU25190 | Menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit); Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. | Cytochrome c550; Not essential for growth on minimal or rich media. | 0.986 |
qcrA | resA | BSU22560 | BSU23150 | Menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit); Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. | Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily. | 0.617 |
qcrA | resB | BSU22560 | BSU23140 | Menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit); Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. | Factor required for cytochrome c synthesis; Required for the biogenesis of c-type cytochromes. | 0.782 |