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mdxL mdxL mdxK mdxK mdxD mdxD mdxJ mdxJ mdxF mdxF mdxM mdxM mdxG mdxG mdxE mdxE amyE amyE sacA sacA malP malP
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mdxLOligo-1,4-1,6-alpha-glucosidase (sucrase-maltase-isomaltase); Hydrolyzes various disaccharides such as sucrose, maltose, and isomaltose with different efficiencies. Also hydrolyzes longer maltodextrins from maltotriose up to maltohexaose, but not maltoheptaose, palatinose, isomaltotriose, or isomaltotetraose. Belongs to the glycosyl hydrolase 13 family. (561 aa)    
Predicted Functional Partners:
mdxK
Maltose phosphorylase; Catalyzes the phosphorolysis of maltose, leading to the formation of glucose and glucose 1-P.
  
  
 0.990
mdxD
Maltogenic alpha-amylase; Hydrolyzes beta-cyclodextrin to maltose and glucose, soluble starch to maltose and glucose, and pullulan to panose with trace amounts of maltose and glucose. It is also able to hydrolyze acarbose. Can also exhibit a transglycosylation activity transferring glucose or maltose to another moiety of sugars by forming alpha-(1,6)- and alpha- (1,3)-glycosidic linkages upon the hydrolysis of substrate at concentrations of 5% or higher (By similarity); Belongs to the glycosyl hydrolase 13 family. BbmA subfamily.
 
 
0.982
mdxJ
Putative component of maltodextrin transporter; Could have a role in maltodextrin utilization.
  
  
 0.980
mdxF
Maltodextrin ABC transport system (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable).
  
  
 0.972
mdxM
Beta-phosphoglucomutase; Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and forming beta-D-glucose 1,6- (bis)phosphate (beta-G16P) as an intermediate. The beta- phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose (By similarity).
  
  
 0.970
mdxG
Maltodextrin ABC transporter (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable).
  
  
 0.970
mdxE
Maltose/maltodextrin-binding lipoprotein; Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity, but is not involved in its uptake; Belongs to the bacterial solute-binding protein 1 family.
  
  
 0.947
amyE
Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family.
  
 
 0.946
sacA
Sucrase-6-phosphate hydrolase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the glycosyl hydrolase 32 family.
  
 
 0.945
malP
Phosphotransferase system (PTS) maltose-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport.
  
  
 0.912
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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