node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HemD | cysG | aq_1771 | aq_1237 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Siroheme synthase. | 0.404 |
HemD | gsa | aq_1771 | aq_816 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde aminotransferase. | 0.687 |
HemD | hemA | aq_1771 | aq_1279 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.768 |
HemD | hemB | aq_1771 | aq_2109 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | 0.952 |
HemD | hemC | aq_1771 | aq_263 | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
aq_818 | dfp | aq_818 | aq_815 | Putative protein. | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.572 |
aq_818 | gsa | aq_818 | aq_816 | Putative protein. | Glutamate-1-semialdehyde aminotransferase. | 0.782 |
aq_818 | lnt | aq_818 | aq_819 | Putative protein. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.773 |
cysG | HemD | aq_1237 | aq_1771 | Siroheme synthase. | Putative protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.404 |
cysG | gsa | aq_1237 | aq_816 | Siroheme synthase. | Glutamate-1-semialdehyde aminotransferase. | 0.876 |
cysG | hemA | aq_1237 | aq_1279 | Siroheme synthase. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.889 |
cysG | hemC | aq_1237 | aq_263 | Siroheme synthase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.845 |
dfp | aq_818 | aq_815 | aq_818 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative protein. | 0.572 |
dfp | gsa | aq_815 | aq_816 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Glutamate-1-semialdehyde aminotransferase. | 0.602 |
dfp | lnt | aq_815 | aq_819 | Pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.567 |
fabD | fabF | aq_892 | aq_1717 | malonyl-CoA:Acyl carrier protein transacylase. | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.999 |
fabD | gsa | aq_892 | aq_816 | malonyl-CoA:Acyl carrier protein transacylase. | Glutamate-1-semialdehyde aminotransferase. | 0.822 |
fabD | hemB | aq_892 | aq_2109 | malonyl-CoA:Acyl carrier protein transacylase. | Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | 0.731 |
fabF | fabD | aq_1717 | aq_892 | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | malonyl-CoA:Acyl carrier protein transacylase. | 0.999 |
fabF | gsa | aq_1717 | aq_816 | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Glutamate-1-semialdehyde aminotransferase. | 0.765 |