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luxS luxS mtnN mtnN swp_0992 swp_0992 swp_3096 swp_3096 swp_4557 swp_4557 swp_0174 swp_0174 swp_1841 swp_1841 swp_4408 swp_4408 swp_3649 swp_3649 swp_0635 swp_0635 swp_1961 swp_1961
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
luxSLuxS protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (169 aa)    
Predicted Functional Partners:
mtnN
Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.987
swp_0992
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.950
swp_3096
Cystathionine beta-lyase, bacterial.
 
 
 0.944
swp_4557
Cystathionine gamma-synthase.
 
 
 0.940
swp_0174
Methionine synthase, vitamin-B12 independent.
    
 0.934
swp_1841
S-adenosylhomocysteine hydrolase.
    
 0.919
swp_4408
O-acetylhomoserine/O-acetylserine sulfhydrylase.
     
 0.909
swp_3649
Aminotransferase, putative.
     
  0.900
swp_0635
Cysteine synthase.
  
 
 0.868
swp_1961
Cysteine synthase K/M:Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.868
Your Current Organism:
Shewanella piezotolerans
NCBI taxonomy Id: 225849
Other names: S. piezotolerans WP3, Shewanella piezotolerans WP3, Shewanella piezotolerans str. WP3, Shewanella piezotolerans strain WP3, Shewanella sp. WP3
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