STRINGSTRING
rpoS rpoS rpoB rpoB dnaG dnaG rpoA rpoA rpoC rpoC rpoZ rpoZ oxyR oxyR CBU_1319 CBU_1319 sspA sspA surE surE CBU_1670 CBU_1670
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoSRNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. Belongs to the sigma-70 factor family. RpoS subfamily. (352 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.928
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.897
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.869
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.867
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.792
oxyR
Hydrogen peroxide-inducible genes activator; Belongs to the LysR transcriptional regulatory family.
      
 0.769
CBU_1319
Transcriptional regulator, MerR family.
  
 
 0.648
sspA
Stringent starvation protein A; Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme; Belongs to the GST superfamily. HSP26 family.
    
 
 0.620
surE
Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.614
CBU_1670
Peptidoglycan-specific endopeptidase, M23 family.
       0.601
Your Current Organism:
Coxiella burnetii
NCBI taxonomy Id: 227377
Other names: C. burnetii RSA 493, Coxiella burnetii RSA 493, Coxiella burnetii str. RSA 493
Server load: low (30%) [HD]