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deoD deoD HSM_0450 HSM_0450 tdk tdk cdd cdd HSM_1981 HSM_1981 apt apt HSM_0762 HSM_0762 gpt gpt HSM_1893 HSM_1893 upp upp pyrR pyrR
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
deoDTIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: hso:HS_0288 purine-nucleoside phosphorylase. (238 aa)    
Predicted Functional Partners:
HSM_0450
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
 
  
0.932
tdk
PFAM: thymidine kinase; KEGG: hso:HS_0410 thymidine kinase.
  
 
 0.928
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
  
 
 0.924
HSM_1981
TIGRFAM: cytidyltransferase-related domain; nicotinamide-nucleotide adenylyltransferase; PFAM: helix-turn-helix domain protein; cytidylyltransferase; KEGG: hso:HS_0087 transcriptional regulator.
    
 0.913
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.912
HSM_0762
TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: hso:HS_0463 hypoxanthine phosphoribosyltransferase (HPRT); Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.912
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
 0.912
HSM_1893
PFAM: Nicotinate phosphoribosyltransferase and related; KEGG: hso:HS_0002 nicotinate phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.911
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
  0.909
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
  0.900
Your Current Organism:
Histophilus somni
NCBI taxonomy Id: 228400
Other names: H. somni 2336, Haemophilus somnus 2336, Histophilus somni 2336, Histophilus somni str. 2336
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