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ppnK ppnK nadE nadE nadD nadD HNE_0882 HNE_0882 pntAB pntAB pntAA pntAA pntB pntB HNE_2004 HNE_2004 HNE_0664 HNE_0664 maeB maeB surE surE
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
ppnKATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (255 aa)    
Predicted Functional Partners:
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.968
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.945
HNE_0882
Transcriptional regulator, Sir2 family; Identified by match to protein family HMM PF02146.
  
 
 0.939
pntAB
NAD(P) transhydrogenase, alpha subunit part 2; Identified by similarity to SP:Q59764.
     
 0.914
pntAA
NAD(P) transhydrogenase, alpha subunit part 1; Identified by similarity to SP:Q60164; match to protein family HMM PF01262; match to protein family HMM PF05222.
     
 0.913
pntB
NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.906
HNE_2004
Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444.
     
 0.904
HNE_0664
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
     
 0.903
maeB
NADP-dependent malic enzyme; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949.
 
 
 
 0.730
surE
Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.664
Your Current Organism:
Hyphomonas neptunium
NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444
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