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purQ purQ purS purS purL purL purF purF purM purM purD purD purN purN purC purC purE purE purK purK purH purH
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query proteins and first shell of interactors
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purQPhosphoribosylformylglycinamidine (FGAM) synthasecomponent I (glutamine amidotransferase domain); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS int [...] (228 aa)    
Predicted Functional Partners:
purS
Phosphoribosylformylglycinamidine (FGAM) synthasePurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...]
 
 0.999
purL
Phosphoribosylformylglycinamidine (FGAM) synthasecomponent II (synthetase domain); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with Pur [...]
 0.999
purF
Phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 
 0.999
purM
Phosphoribosylaminoimidazole synthetase (hosphoribosylformylglycinamidine cyclo-ligase).
 
 0.999
purD
Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family.
  
 0.999
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 
 0.998
purC
Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family.
 
  
 0.993
purE
Phosphoribosylaminoimidazole carboxylasecatalytic chain; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
  
 0.990
purK
Phosphoribosylaminoimidazole carboxylasecarbon dioxide-fixation chain; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 
  
 0.984
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase (bifunctional purine biosynthesis protein).
 
  
 0.983
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
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