STRINGSTRING
gmk gmk rpoZ rpoZ guaA guaA apt apt GK1166 GK1166 GK0061 GK0061 GK2739 GK2739 GK2578 GK2578 ndk ndk GK3019 GK3019 GK0911 GK0911
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (205 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase omega subunit (transcriptase omega chain); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.988
guaA
GMP synthetase (glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
 
 
 0.971
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.961
GK1166
Hypothetical conserved protein; Belongs to the RemA family.
  
    0.954
GK0061
Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.940
GK2739
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.939
GK2578
GTP pyrophosphokinase (ppGpp synthetase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.931
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.928
GK3019
Hypothetical conserved protein.
  
 
 0.918
GK0911
Ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.913
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
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