STRINGSTRING
RB11945 RB11945 acs acs RB11943 RB11943 fba fba RB11942 RB11942 dnaK-4 dnaK-4 ctaD ctaD nrfA nrfA RB10805 RB10805 RB11946 RB11946 RB11941 RB11941
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB11945Probable aldehyde dehydrogenase (NAD+); PMID: 7934828 PMID: 9384377 PMID: 89229122 best DB hits: BLAST: pir:T03560; probable aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) -; E=1e-31 pir:D83600; probable aldehyde dehydrogenase PA0366 [imported] -; E=3e-31 gb:AAG20575.1; (AE005128) aldehyde dehydrogenase (retinol); AldY1; E=5e-31 COG: PA0366; COG1012 NAD-dependent aldehyde dehydrogenases; E=3e-32 PFAM: PF00171; Aldehyde dehydrogenase family; E=2.5e-20. (556 aa)    
Predicted Functional Partners:
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.665
RB11943
Phytoene dehydrogenase; PMID: 7588751 PMID: 2263648 best DB hits: BLAST: swissprot:P54979; CRTJ_MYXXA PHYTOENE DEHYDROGENASE (PHYTOENE; E=2e-50 embl:CAA66626.1; (X97985) ORF3 [Staphylococcus aureus]; E=2e-48 pir:T31463; probable diapophytoene dehydrogenase crtN -; E=9e-47 COG: VNG1684G; COG1233 Phytoene dehydrogenase and related proteins; E=4e-41 PFAM: PF01266; D-amino acid oxidase; E=7.4e-05 PF01494; FAD binding domain; E=1.7e-06 PF02254; KTN NAD-binding domain; E=0.026.
 
  
 0.656
fba
Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
  
 0.646
RB11942
Conserved hypothetical protein-putative acyltransferase; PMID: 7588751 best DB hits: BLAST: pir:S68196; hypothetical protein 9 - Myxococcus xanthus -----; E=5e-06 PFAM: PF01553; Acyltransferase; E=0.013.
 
   
 0.635
dnaK-4
DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.626
ctaD
Cytochrome oxidase subunit I; PMID: 20576172 best DB hits: BLAST: embl:CAC08532.1; (AJ249578) cytochrome oxidase subunit I; E=1e-146 ddbj:BAA06976.1; (D32217) cytochrome c oxidase-like protein; E=1e-122 swissprot:Q06473; COX1_SYNY3 CYTOCHROME C OXIDASE POLYPEPTIDE I; E=3e-99 COG: slr1137; COG0843 Heme/copper-type cytochrome/quinol oxidases,; E=1e-100 RP405; COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit; E=3e-93 BS_ctaD; COG0843 Heme/copper-type cytochrome/quinol oxidases,; E=4e-91 PFAM: PF00115; Cytochrome C and Quinol oxidase pol; E=8.3e-185; Belongs to the heme-copper [...]
   
  
 0.614
nrfA
Catalytic subunit of cytochrome c nitrite reductase; PMID: 20138370 best DB hits: BLAST: pir:B81280; probable periplasmic cytochrome C Cj1357c [imported] -; E=1e-50 embl:CAB53160.1; (AJ245540) catalytic subunit of cytochrome c; E=5e-42 embl:CAB37320.1; (AJ133037) cytochrome c nitrite reductase; E=5e-37 COG: Cj1357c; COG3303 Nitrite reductase, periplasmic cytochrome c subunit; E=9e-52 PFAM: PF02335; Cytochrome c552; E=0.032; Belongs to the cytochrome c-552 family.
      
 0.610
RB10805
Putative iron alcohol dehydrogenase; PMID: 88038383 best DB hits: BLAST: swissprot:Q09669; ADHF_SCHPO PUTATIVE IRON ALCOHOL DEHYDROGENASE; E=5e-46 gb:AAD43989.1; U59485_16 (U59485) AttL [Agrobacterium tumefaciens]; E=5e-45 gb:AAG58733.1; AE005585_7 (AE005585) putative oxidoreductase; E=6e-42 COG: yiaY; COG1454 Alcohol dehydrogenase IV; E=3e-42 PFAM: PF00465; Iron-containing alcohol dehydrogenas; E=3.3e-58.
 
 0.604
RB11946
Best DB hits: BLAST: ddbj:BAB13707.1; (AB040150) thermophilic NAD(P)H-flavin; E=2e-18 pir:B72384; bacterioferritin comigratory proteinNADH dehydrogenase; E=5e-08 swissprot:O26223; Y120_METTH PUTATIVE NADH DEHYDROGENASENAD(P)H; E=0.003 COG: TM0386_2; COG0778 Nitroreductase; E=5e-09 PFAM: PF00881; Nitroreductase family; E=3.3e-13.
  
  
 0.591
RB11941
Conserved hypothetical protein-putative glycosyl transferase; PMID: 8905231 best DB hits: BLAST: pir:A75561; conserved hypothetical protein - Deinococcus radiodurans; E=6e-16 embl:CAA66627.1; (X97985) ORF4 [Staphylococcus aureus]; E=1e-13 pir:S76793; hypothetical protein - Synechocystis sp. (strain PCC; E=3e-11 COG: DR0089; COG0463 Glycosyltransferases involved in cell wall; E=6e-17 MTH548; COG0784 CheY-like receiver domains; E=1e-06 PAB1246; COG1215 Glycosyltransferases, probably involved in cell; E=2e-06 PFAM: PF00535; Glycosyl transferase; E=3.5e-23.
       0.586
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.