node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFE_2662 | dapB | AFE_2662 | AFE_2663 | Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.723 |
AFE_2662 | dcd | AFE_2662 | AFE_2660 | Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.702 |
AFE_2662 | dnaJ | AFE_2662 | AFE_2664 | Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.689 |
AFE_2662 | dnaK | AFE_2662 | AFE_2665 | Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992. | Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.517 |
AFE_2662 | mrp | AFE_2662 | AFE_2661 | Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992. | Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.781 |
dapB | AFE_2662 | AFE_2663 | AFE_2662 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992. | 0.723 |
dapB | dcd | AFE_2663 | AFE_2660 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.605 |
dapB | dnaJ | AFE_2663 | AFE_2664 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.943 |
dapB | dnaK | AFE_2663 | AFE_2665 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.661 |
dapB | mrp | AFE_2663 | AFE_2661 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.736 |
dcd | AFE_2662 | AFE_2660 | AFE_2662 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Antibiotic biosynthesis monooxygenase family protein; Identified by match to protein family HMM PF03992. | 0.702 |
dcd | dapB | AFE_2660 | AFE_2663 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.605 |
dcd | dnaJ | AFE_2660 | AFE_2664 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.641 |
dcd | dnaK | AFE_2660 | AFE_2665 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Chaperone protein Dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.456 |
dcd | dut | AFE_2660 | AFE_0356 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Deoxyuridine 5`-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.926 |
dcd | mrp | AFE_2660 | AFE_2661 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.721 |
dcd | ndk | AFE_2660 | AFE_1929 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.924 |
dcd | nrdD | AFE_2660 | AFE_2718 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Anaerobic ribonucleoside-triphosphate reductase, alpha subunit; Identified by similarity to GB:AAP85992.1; match to protein family HMM TIGR02487. | 0.901 |
dcd | pyrG | AFE_2660 | AFE_0847 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.924 |
dcd | rfbD | AFE_2660 | AFE_0442 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.612 |