node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR_0179 | glpK | DR_0179 | DR_1928 | Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.736 |
DR_0402 | DR_0647 | DR_0402 | DR_0647 | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 GB:AL123456 percent identity: 49.61; identified by sequence similarity; putative. | Cell division cycle protein 48-related protein; Similar to SP:P54774 PID:862480 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the AAA ATPase family. | 0.523 |
DR_0402 | glpK | DR_0402 | DR_1928 | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 GB:AL123456 percent identity: 49.61; identified by sequence similarity; putative. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.992 |
DR_0647 | DR_0402 | DR_0647 | DR_0402 | Cell division cycle protein 48-related protein; Similar to SP:P54774 PID:862480 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the AAA ATPase family. | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 GB:AL123456 percent identity: 49.61; identified by sequence similarity; putative. | 0.523 |
DR_0647 | glpK | DR_0647 | DR_1928 | Cell division cycle protein 48-related protein; Similar to SP:P54774 PID:862480 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the AAA ATPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.682 |
DR_1019 | DR_1929 | DR_1019 | DR_1929 | Glycerol-3-phosphate dehydrogenase; Similar to GB:AE000783 percent identity: 68.44; identified by sequence similarity; putative. | Glycerol uptake facilitator protein; Similar to GB:AE000783 percent identity: 78.23; identified by sequence similarity; putative; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.928 |
DR_1019 | glpK | DR_1019 | DR_1928 | Glycerol-3-phosphate dehydrogenase; Similar to GB:AE000783 percent identity: 68.44; identified by sequence similarity; putative. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.997 |
DR_1019 | plsY1 | DR_1019 | DR_2021 | Glycerol-3-phosphate dehydrogenase; Similar to GB:AE000783 percent identity: 68.44; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.908 |
DR_1019 | plsY2 | DR_1019 | DR_2270 | Glycerol-3-phosphate dehydrogenase; Similar to GB:AE000783 percent identity: 68.44; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.908 |
DR_1929 | DR_1019 | DR_1929 | DR_1019 | Glycerol uptake facilitator protein; Similar to GB:AE000783 percent identity: 78.23; identified by sequence similarity; putative; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol-3-phosphate dehydrogenase; Similar to GB:AE000783 percent identity: 68.44; identified by sequence similarity; putative. | 0.928 |
DR_1929 | glpK | DR_1929 | DR_1928 | Glycerol uptake facilitator protein; Similar to GB:AE000783 percent identity: 78.23; identified by sequence similarity; putative; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.996 |
DR_A0310 | glpK | DR_A0310 | DR_1928 | Carboxylase; Similar to PID:550486 percent identity: 61.05; identified by sequence similarity; putative. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.659 |
DR_A0310 | gltA | DR_A0310 | DR_0757 | Carboxylase; Similar to PID:550486 percent identity: 61.05; identified by sequence similarity; putative. | Citrate synthase; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect (By similarity). | 0.723 |
DR_A0310 | hbd | DR_A0310 | DR_1068 | Carboxylase; Similar to PID:550486 percent identity: 61.05; identified by sequence similarity; putative. | 3-hydroxybutyryl-CoA dehydrogenase; Similar to SP:P45856 PID:881605 PID:1303932 GB:AL009126 percent identity: 69.78; identified by sequence similarity; putative; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.484 |
glpK | DR_0179 | DR_1928 | DR_0179 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.736 |
glpK | DR_0402 | DR_1928 | DR_0402 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 GB:AL123456 percent identity: 49.61; identified by sequence similarity; putative. | 0.992 |
glpK | DR_0647 | DR_1928 | DR_0647 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Cell division cycle protein 48-related protein; Similar to SP:P54774 PID:862480 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the AAA ATPase family. | 0.682 |
glpK | DR_1019 | DR_1928 | DR_1019 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Glycerol-3-phosphate dehydrogenase; Similar to GB:AE000783 percent identity: 68.44; identified by sequence similarity; putative. | 0.997 |
glpK | DR_1929 | DR_1928 | DR_1929 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Glycerol uptake facilitator protein; Similar to GB:AE000783 percent identity: 78.23; identified by sequence similarity; putative; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.996 |
glpK | DR_A0310 | DR_1928 | DR_A0310 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Carboxylase; Similar to PID:550486 percent identity: 61.05; identified by sequence similarity; putative. | 0.659 |