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ppc ppc eno eno pckA pckA mdh mdh pykA pykA pykF pykF ppsA ppsA aceB aceB fdoH fdoH gltB gltB amiF amiF
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
ppcPhosphoenolpyruvate carboxylase (PEPCASE) (PEPC); Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (878 aa)    
Predicted Functional Partners:
eno
Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 
 0.929
pckA
Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.927
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
     
 0.927
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
     
 0.915
pykF
Pyruvate kinase I (PK-1); Belongs to the pyruvate kinase family.
     
 0.915
ppsA
Phosphoenolpyruvate synthase (PEP synthase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.915
aceB
Malate synthase A (MSA).
     
 0.854
fdoH
Formate dehydrogenase iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
     
 0.836
gltB
Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain).
  
  
 0.826
amiF
Formamidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
  
  
  0.823
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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