node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CV_0748 | fmt | CV_0748 | CV_4264 | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.909 |
CV_0748 | fmt2 | CV_0748 | CV_2818 | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | methionyl-tRNA formyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | 0.923 |
CV_0748 | folD | CV_0748 | CV_1925 | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.960 |
CV_0748 | gcvT | CV_0748 | CV_3431 | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.920 |
CV_0748 | glyA | CV_0748 | CV_1286 | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
CV_0748 | purN | CV_0748 | CV_3616 | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.921 |
fmt | CV_0748 | CV_4264 | CV_0748 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | 0.909 |
fmt | fmt2 | CV_4264 | CV_2818 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | methionyl-tRNA formyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | 0.945 |
fmt | folD | CV_4264 | CV_1925 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.965 |
fmt | gcvT | CV_4264 | CV_3431 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.920 |
fmt | glyA | CV_4264 | CV_1286 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
fmt | purH | CV_4264 | CV_0546 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0138. | 0.474 |
fmt | purN | CV_4264 | CV_3616 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.921 |
fmt2 | CV_0748 | CV_2818 | CV_0748 | methionyl-tRNA formyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | 0.923 |
fmt2 | fmt | CV_2818 | CV_4264 | methionyl-tRNA formyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.945 |
fmt2 | folD | CV_2818 | CV_1925 | methionyl-tRNA formyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.960 |
fmt2 | gcvT | CV_2818 | CV_3431 | methionyl-tRNA formyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.920 |
fmt2 | glyA | CV_2818 | CV_1286 | methionyl-tRNA formyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
fmt2 | purN | CV_2818 | CV_3616 | methionyl-tRNA formyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.921 |
folD | CV_0748 | CV_1925 | CV_0748 | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Probable transformylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0223. | 0.960 |