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bioB bioB bioD bioD bioA bioA bioF bioF birA birA CV_1436 CV_1436 argD argD CV_2025 CV_2025 CV_0803 CV_0803 CV_0021 CV_0021 kbl kbl
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (327 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 0.998
bioA
Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0161; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.994
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
 0.962
birA
Biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.954
CV_1436
Probable b-alanine-pyruvate transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0161; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.950
argD
Acetylornithine aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0161; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.885
CV_2025
Probable aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0161.
 
  
 0.874
CV_0803
Probable 5-aminolevulinate synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0156.
  
 0.837
CV_0021
Probable aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0156.
 
  
 0.830
kbl
Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
  
 0.805
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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