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ABK72306.1 ABK72306.1 pknB pknB pknA pknA pbpA pbpA ABK71056.1 ABK71056.1 fhaB fhaB ABK70730.1 ABK70730.1 ABK74362.1 ABK74362.1 ABK71684.1 ABK71684.1 ABK74946.1 ABK74946.1 sun sun
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ABK72306.1Protein phosphatase 2C; Identified by match to protein family HMM PF00481. (512 aa)    
Predicted Functional Partners:
pknB
Serine-threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins (By similarity). Probably phosphorylates RseA.
 
 0.998
pknA
Serine/threonine protein kinase PknA; Identified by match to protein family HMM PF00069.
 
 0.994
pbpA
Penicillin binding protein transpeptidase domain protein; Cell wall formation. Plays an important role in cell division and cell shape maintenance by cross-linking adjacent peptidoglycan chains through transpeptidation.
  
  
 0.969
ABK71056.1
Cell cycle protein, FtsW/RodA/SpoVE family protein; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.
 
  
 0.958
fhaB
FHA domain protein; Regulates growth and cell division. Probably required for divisomal protein assembly under oxidative stress.
 
 
 0.957
ABK70730.1
Transketolase, central region; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM PF02780.
  
 0.957
ABK74362.1
Serine/threonine-protein kinase PK-1; Identified by match to protein family HMM PF00069; match to protein family HMM PF01163.
 
 0.906
ABK71684.1
Serine/threonine-protein kinase PknD; Identified by match to protein family HMM PF00069.
 
 0.889
ABK74946.1
Serine/threonine protein kinase PksC; Identified by match to protein family HMM PF00069.
 
 0.888
sun
Ribosomal RNA small subunit methyltransferase B; Identified by match to protein family HMM PF01029; match to protein family HMM PF01189; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
 
 0.880
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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