node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK72654.1 | senX3 | MSMEG_4990 | MSMEG_0936 | DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.951 |
ABK72873.1 | prrA | MSMEG_0244 | MSMEG_5662 | Two component response transcriptional regulatory protein prra; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | DNA-binding response regulator PrrA; Identified by similarity to SP:Q10531; match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.905 |
ABK72873.1 | senX3 | MSMEG_0244 | MSMEG_0936 | Two component response transcriptional regulatory protein prra; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.901 |
ABK73706.1 | ABK74820.1 | MSMEG_2916 | MSMEG_5396 | DNA-binding response regulator, PhoP family protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | KDP operon transcriptional regulatory protein KdpE; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.881 |
ABK73706.1 | senX3 | MSMEG_2916 | MSMEG_0936 | DNA-binding response regulator, PhoP family protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.890 |
ABK74820.1 | ABK73706.1 | MSMEG_5396 | MSMEG_2916 | KDP operon transcriptional regulatory protein KdpE; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | DNA-binding response regulator, PhoP family protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.881 |
ABK74820.1 | senX3 | MSMEG_5396 | MSMEG_0936 | KDP operon transcriptional regulatory protein KdpE; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.873 |
mprA | senX3 | MSMEG_5488 | MSMEG_0936 | DNA-binding response regulator; Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity). | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.957 |
mtrA | senX3 | MSMEG_1874 | MSMEG_0936 | DNA-binding response regulator MtrA; Member of the two-component regulatory system MtrA/MtrB, responding to environmental signals (Probable). Controls expression of a number of genes including dnaA, ripA, fbpB and probably itself. Probably plays a role in cell division. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.963 |
phoP | senX3 | MSMEG_5872 | MSMEG_0936 | DNA-binding response regulator PhoP; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.951 |
prrA | ABK72873.1 | MSMEG_5662 | MSMEG_0244 | DNA-binding response regulator PrrA; Identified by similarity to SP:Q10531; match to protein family HMM PF00072; match to protein family HMM PF00486. | Two component response transcriptional regulatory protein prra; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.905 |
prrA | senX3 | MSMEG_5662 | MSMEG_0936 | DNA-binding response regulator PrrA; Identified by similarity to SP:Q10531; match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.941 |
regX3 | senX3 | MSMEG_0937 | MSMEG_0936 | DNA-binding response regulator RegX3; Part of the two-component regulatory system SenX3/RegX3. Once phosphorylated by SenX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.999 |
resD | senX3 | MSMEG_0994 | MSMEG_0936 | DNA-binding response regulator ResD; Identified by similarity to SP:P35163; match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | 0.918 |
senX3 | ABK72654.1 | MSMEG_0936 | MSMEG_4990 | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.951 |
senX3 | ABK72873.1 | MSMEG_0936 | MSMEG_0244 | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | Two component response transcriptional regulatory protein prra; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.901 |
senX3 | ABK73706.1 | MSMEG_0936 | MSMEG_2916 | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | DNA-binding response regulator, PhoP family protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.890 |
senX3 | ABK74820.1 | MSMEG_0936 | MSMEG_5396 | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | KDP operon transcriptional regulatory protein KdpE; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.873 |
senX3 | mprA | MSMEG_0936 | MSMEG_5488 | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | DNA-binding response regulator; Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity). | 0.957 |
senX3 | mtrA | MSMEG_0936 | MSMEG_1874 | Sensor histidine kinase SenX3; Part of the two-component regulatory system SenX3/RegX3. Phosphorylates RegX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to SenX3 by the PstSCAB phosphate transporter system. | DNA-binding response regulator MtrA; Member of the two-component regulatory system MtrA/MtrB, responding to environmental signals (Probable). Controls expression of a number of genes including dnaA, ripA, fbpB and probably itself. Probably plays a role in cell division. | 0.963 |