node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPA1229 | hmgA | RPA1229 | RPA4672 | Probable aerobic phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.719 |
RPA3443 | hmgA | RPA3443 | RPA4672 | Possible isomerase/decarboxylase. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.711 |
RPA3443 | hpd | RPA3443 | RPA0005 | Possible isomerase/decarboxylase. | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.501 |
RPA3443 | maiA | RPA3443 | RPA4671 | Possible isomerase/decarboxylase. | Putative maleylacetoacetate isomerase. | 0.409 |
RPA4674 | RPA4675 | RPA4674 | RPA4675 | Conserved hypothetical protein. | Possible 3-(3-hydroxy-phenyl)propionate hydroxylase. | 0.898 |
RPA4674 | cphA1 | RPA4674 | RPA4673 | Conserved hypothetical protein. | Putative beta lactamase precursor. | 0.890 |
RPA4674 | fahA | RPA4674 | RPA4670 | Conserved hypothetical protein. | Fumarylacetoacetate hydrolase. | 0.457 |
RPA4674 | hmgA | RPA4674 | RPA4672 | Conserved hypothetical protein. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.707 |
RPA4674 | hpd | RPA4674 | RPA0005 | Conserved hypothetical protein. | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.501 |
RPA4674 | maiA | RPA4674 | RPA4671 | Conserved hypothetical protein. | Putative maleylacetoacetate isomerase. | 0.581 |
RPA4675 | RPA4674 | RPA4675 | RPA4674 | Possible 3-(3-hydroxy-phenyl)propionate hydroxylase. | Conserved hypothetical protein. | 0.898 |
RPA4675 | cphA1 | RPA4675 | RPA4673 | Possible 3-(3-hydroxy-phenyl)propionate hydroxylase. | Putative beta lactamase precursor. | 0.960 |
RPA4675 | fahA | RPA4675 | RPA4670 | Possible 3-(3-hydroxy-phenyl)propionate hydroxylase. | Fumarylacetoacetate hydrolase. | 0.640 |
RPA4675 | hmgA | RPA4675 | RPA4672 | Possible 3-(3-hydroxy-phenyl)propionate hydroxylase. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.825 |
RPA4675 | hpd | RPA4675 | RPA0005 | Possible 3-(3-hydroxy-phenyl)propionate hydroxylase. | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.565 |
RPA4675 | maiA | RPA4675 | RPA4671 | Possible 3-(3-hydroxy-phenyl)propionate hydroxylase. | Putative maleylacetoacetate isomerase. | 0.665 |
cphA1 | RPA4674 | RPA4673 | RPA4674 | Putative beta lactamase precursor. | Conserved hypothetical protein. | 0.890 |
cphA1 | RPA4675 | RPA4673 | RPA4675 | Putative beta lactamase precursor. | Possible 3-(3-hydroxy-phenyl)propionate hydroxylase. | 0.960 |
cphA1 | fahA | RPA4673 | RPA4670 | Putative beta lactamase precursor. | Fumarylacetoacetate hydrolase. | 0.586 |
cphA1 | hmgA | RPA4673 | RPA4672 | Putative beta lactamase precursor. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.873 |