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msrA-2 msrA-2 msrB msrB dsbE dsbE polA polA msrA msrA cmoA cmoA metH metH Psyc_1951 Psyc_1951 macB macB Psyc_1555 Psyc_1555 Psyc_1649 Psyc_1649
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
msrA-2Probable peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (173 aa)    
Predicted Functional Partners:
msrB
Conserved hypothetical protein; Have a SelR domain; Belongs to the MsrB Met sulfoxide reductase family.
 
 0.990
dsbE
Probable periplasmic protein thiol:disulfide oxidoreductase DsbE.
   
 0.899
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.845
msrA
Probable peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 
0.566
cmoA
Probable methyltransferase protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
       0.469
metH
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.468
Psyc_1951
Hypothetical protein.
  
    0.434
macB
ABC macrolide efflux transporter MacB, fused ATPase and inner membrane domains; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
     
 0.430
Psyc_1555
Probable glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 
 0.426
Psyc_1649
Conserved hypothetical protein.
  
 
 0.426
Your Current Organism:
Psychrobacter arcticus
NCBI taxonomy Id: 259536
Other names: P. arcticus 273-4, Psychrobacter arcticus 273-4, Psychrobacter arcticus str. 273-4, Psychrobacter arcticus strain 273-4, Psychrobacter sp. 273-4
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