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rtcA rtcA rps6e rps6e rps4p rps4p rps11p rps11p csl4 csl4 Mbur_1562 Mbur_1562 rrp42 rrp42 rrp4 rrp4 rtcB rtcB rps3ae rps3ae Mbur_0948 Mbur_0948
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rtcARNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (331 aa)    
Predicted Functional Partners:
rps6e
SSU ribosomal protein S6E; Evidence code ER2; Belongs to the eukaryotic ribosomal protein eS6 family.
    
 0.975
rps4p
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.974
rps11p
SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
    
  0.960
csl4
Archaeal exosome RNA binding protein CSL4 with cold-sensitive-phenotype rescue activity; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
  
  0.949
Mbur_1562
Pre-mRNA processing ribonucleoprotein; Evidence code ER3.
 
 
 0.946
rrp42
Archaeal exosome complex exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
  
  0.927
rrp4
Archaeal exosome complex RNA-binding protein 4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
  
  0.911
rtcB
UPF0027-domain protein; Evidence code ER4; Belongs to the RtcB family.
 
  
 0.908
rps3ae
SSU ribosomal protein S3Ae; Evidence code ER2; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
  0.902
Mbur_0948
KH type RNA-binding protein; Evidence code ER3.
   
 
 0.900
Your Current Organism:
Methanococcoides burtonii
NCBI taxonomy Id: 259564
Other names: M. burtonii DSM 6242, Methanococcoides burtonii DSM 6242, Methanococcoides burtonii str. DSM 6242
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