STRINGSTRING
AEB43180.1 AEB43180.1 AEB42428.1 AEB42428.1 AEB47022.1 AEB47022.1 AEB43670.1 AEB43670.1 AEB45841.1 AEB45841.1 AEB42427.1 AEB42427.1 ku ku AEB43179.1 AEB43179.1 AEB47977.1 AEB47977.1 AEB46650.1 AEB46650.1 polA polA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB43180.1DNA ligase D, 3'-phosphoesterase domain-containing protein; COG1793 ATP-dependent DNA ligase. (348 aa)    
Predicted Functional Partners:
AEB42428.1
DNA polymerase ligd, polymerase domain protein; COG3285 Predicted eukaryotic-type DNA primase.
  
 0.998
AEB47022.1
DNA polymerase LigD polymerase subunit; COG3285 Predicted eukaryotic-type DNA primase.
  
 0.997
AEB43670.1
DNA primase, small subunit; COG3285 Predicted eukaryotic-type DNA primase.
   
 0.977
AEB45841.1
COG3285 Predicted eukaryotic-type DNA primase.
   
 0.977
AEB42427.1
DNA polymerase LigD ligase subunit; COG1793 ATP-dependent DNA ligase.
  
  
 
0.925
ku
Ku family containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.844
AEB43179.1
COG0498 Threonine synthase.
       0.737
AEB47977.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.733
AEB46650.1
DNA polymerase III subunit beta; COG0789 Predicted transcriptional regulators.
   
 0.733
polA
DNA polymerase i; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.683
Your Current Organism:
Verrucosispora maris
NCBI taxonomy Id: 263358
Other names: V. maris AB-18-032, Verrucosispora maris AB-18-032, Verrucosispora maris str. AB-18-032, Verrucosispora maris strain AB-18-032, Verrucosispora sp. AB-18-032
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.