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pgk pgk gap gap tpiA tpiA eno eno gpmA gpmA pgi pgi ZMO0152 ZMO0152 ZMO0176 ZMO0176 adhA adhA adhB adhB metK metK
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
pgkKEGG: swi:Swit_2604 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)    
Predicted Functional Partners:
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
 0.999
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.998
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 0.987
pgi
Glucose-6-phosphate isomerase; Provides a gateway for fructose into the Entner-Doudouroff pathway; Belongs to the GPI family.
  
 
 0.974
ZMO0152
TIGRFAM: pyruvate kinase; KEGG: swi:Swit_3121 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
 
 
 0.932
ZMO0176
Transketolase; KEGG: swi:Swit_2601 transketolase; TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; Belongs to the transketolase family.
  
 
 0.849
adhA
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ecg:E2348_C_1612 alcohol dehydrogenase, 1-propanol preferring.
  
 
 0.738
adhB
PFAM: iron-containing alcohol dehydrogenase; KEGG: pmr:PMI0657 probable alcohol dehydrogenase.
  
  
 0.721
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.703
Your Current Organism:
Zymomonas mobilis ZM4
NCBI taxonomy Id: 264203
Other names: Z. mobilis subsp. mobilis ZM4 = ATCC 31821, Zymomonas mobilis subsp. mobilis ATCC 31821, Zymomonas mobilis subsp. mobilis ATCC 31821 = ZM4, Zymomonas mobilis subsp. mobilis ZM4, Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821
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