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mdh mdh fumB fumB citZ citZ fumC fumC aspC aspC mdh-2 mdh-2 sfcA sfcA cit cit ppc ppc icdA icdA gcvP gcvP
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (359 aa)    
Predicted Functional Partners:
fumB
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.997
citZ
InterPro: Citrate synthase; hypothetical protein.
  
 0.985
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.976
aspC
Aspartate aminotransferase.
  
 0.945
mdh-2
Malate dehydrogenase.
  
 0.932
sfcA
InterPro: Malic enzymes; hypothetical protein.
  
 0.932
cit
InterPro: Citrate synthase; hypothetical protein.
  
 0.928
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.925
icdA
Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.921
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.887
Your Current Organism:
Bdellovibrio bacteriovorus HD100
NCBI taxonomy Id: 264462
Other names: B. bacteriovorus HD100, Bdellovibrio bacteriovorus DSM 50701, Bdellovibrio bacteriovorus str. HD100, Bdellovibrio bacteriovorus strain HD100
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