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apt apt guaA guaA purH purH Rru_A0766 Rru_A0766 Rru_A1963 Rru_A1963 Rru_A1958 Rru_A1958 Rru_A0299 Rru_A0299 Rru_A2483 Rru_A2483 mtnP mtnP gmk gmk Rru_A0716 Rru_A0716
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (171 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 0.990
purH
IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase.
  
 0.980
Rru_A0766
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
   
 0.975
Rru_A1963
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.975
Rru_A1958
GMP reductase.
  
 
 0.971
Rru_A0299
Glutamine amidotransferase class-I.
  
 
 0.967
Rru_A2483
5'-Nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.960
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
 
 0.959
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.959
Rru_A0716
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.944
Your Current Organism:
Rhodospirillum rubrum
NCBI taxonomy Id: 269796
Other names: R. rubrum ATCC 11170, Rhodospirillum rubrum ATCC 11170, Rhodospirillum rubrum S1, Rhodospirillum rubrum str. ATCC 11170, Rhodospirillum rubrum strain ATCC 11170
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