node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gmet_0091 | kdsD | Gmet_0091 | Gmet_1278 | Lipid A biosynthesis acyltransferase. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.760 |
Gmet_0091 | kdtA | Gmet_0091 | Gmet_2348 | Lipid A biosynthesis acyltransferase. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.974 |
Gmet_0091 | lpxA-1 | Gmet_0091 | Gmet_2353 | Lipid A biosynthesis acyltransferase. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.899 |
Gmet_0091 | lpxA-2 | Gmet_0091 | Gmet_2567 | Lipid A biosynthesis acyltransferase. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.748 |
Gmet_0091 | lpxB | Gmet_0091 | Gmet_2350 | Lipid A biosynthesis acyltransferase. | Lipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.890 |
Gmet_0091 | lpxC | Gmet_0091 | Gmet_2607 | Lipid A biosynthesis acyltransferase. | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.754 |
Gmet_0091 | lpxD | Gmet_0091 | Gmet_2355 | Lipid A biosynthesis acyltransferase. | UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.896 |
Gmet_0091 | lpxK | Gmet_0091 | Gmet_2347 | Lipid A biosynthesis acyltransferase. | Tetraacyldisaccharide-1-phosphate 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.912 |
kdsD | Gmet_0091 | Gmet_1278 | Gmet_0091 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Lipid A biosynthesis acyltransferase. | 0.760 |
kdsD | kdtA | Gmet_1278 | Gmet_2348 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.883 |
kdsD | lpxA-1 | Gmet_1278 | Gmet_2353 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.854 |
kdsD | lpxA-2 | Gmet_1278 | Gmet_2567 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.851 |
kdsD | lpxB | Gmet_1278 | Gmet_2350 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Lipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.865 |
kdsD | lpxC | Gmet_1278 | Gmet_2607 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.865 |
kdsD | lpxD | Gmet_1278 | Gmet_2355 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.864 |
kdsD | lpxK | Gmet_1278 | Gmet_2347 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide-1-phosphate 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.881 |
kdsD | msbA | Gmet_1278 | Gmet_2349 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Phospholipid/lipopolysaccharide-flipping ABC transporter MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. | 0.419 |
kdtA | Gmet_0091 | Gmet_2348 | Gmet_0091 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Lipid A biosynthesis acyltransferase. | 0.974 |
kdtA | kdsD | Gmet_2348 | Gmet_1278 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.883 |
kdtA | lpxA-1 | Gmet_2348 | Gmet_2353 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.899 |