node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APE_1472 | APE_1686.1 | APE_1472 | APE_1686.1 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | Coenzyme B12-dependent mutase. | 0.916 |
APE_1472 | APE_1687 | APE_1472 | APE_1687 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | Coenzyme B12-dependent mutase. | 0.917 |
APE_1472 | pdhC | APE_1472 | APE_1671 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component. | 0.925 |
APE_1472 | prpB | APE_1472 | APE_0222.1 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | Putative carboxyvinyl-carboxyphosphonate phosphorylmutase; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2- methylisocitrate to yield pyruvate and succinate via an alpha-carboxy- carbanion intermediate. | 0.822 |
APE_1472 | sdhA | APE_1472 | APE_0950.1 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | Succinate dehydrogenase subunit A. | 0.509 |
APE_1472 | sdhC | APE_1472 | APE_0948.1 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | Succinate dehydrogenase subunit C. | 0.446 |
APE_1472 | sucC | APE_1472 | APE_1065.1 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.935 |
APE_1472 | sucD | APE_1472 | APE_1072.1 | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.937 |
APE_1686.1 | APE_1472 | APE_1686.1 | APE_1472 | Coenzyme B12-dependent mutase. | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | 0.916 |
APE_1686.1 | APE_1687 | APE_1686.1 | APE_1687 | Coenzyme B12-dependent mutase. | Coenzyme B12-dependent mutase. | 0.999 |
APE_1686.1 | pdhC | APE_1686.1 | APE_1671 | Coenzyme B12-dependent mutase. | Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component. | 0.834 |
APE_1686.1 | sucC | APE_1686.1 | APE_1065.1 | Coenzyme B12-dependent mutase. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.935 |
APE_1686.1 | sucD | APE_1686.1 | APE_1072.1 | Coenzyme B12-dependent mutase. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.942 |
APE_1687 | APE_1472 | APE_1687 | APE_1472 | Coenzyme B12-dependent mutase. | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | 0.917 |
APE_1687 | APE_1686.1 | APE_1687 | APE_1686.1 | Coenzyme B12-dependent mutase. | Coenzyme B12-dependent mutase. | 0.999 |
APE_1687 | pdhC | APE_1687 | APE_1671 | Coenzyme B12-dependent mutase. | Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component. | 0.834 |
APE_1687 | sucC | APE_1687 | APE_1065.1 | Coenzyme B12-dependent mutase. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.938 |
APE_1687 | sucD | APE_1687 | APE_1072.1 | Coenzyme B12-dependent mutase. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.938 |
pdhC | APE_1472 | APE_1671 | APE_1472 | Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component. | 2-oxoacid:ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives. | 0.925 |
pdhC | APE_1686.1 | APE_1671 | APE_1686.1 | Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component. | Coenzyme B12-dependent mutase. | 0.834 |