STRINGSTRING
gyaR gyaR APE_0996.1 APE_0996.1 loxD loxD APE_0766 APE_0766 APE_2507.1 APE_2507.1 APE_1832 APE_1832 prs prs mdh mdh rpl4p rpl4p pyk pyk APE_1980.1 APE_1980.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
gyaRGlyoxylate reductase. (335 aa)    
Predicted Functional Partners:
APE_0996.1
Glycerate kinase.
 
 
 0.952
loxD
D-lactate dehydrogenase.
   
 0.934
APE_0766
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.921
APE_2507.1
Putative glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
0.920
APE_1832
Acylamino-acid-releasing enzyme.
  
    0.548
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 
 0.529
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. Can utilize both NAD and NADP. Catalytic efficiency for malate oxidation is 3-fold higher with NADP. Belongs to the LDH/MDH superfamily.
  
 
 0.500
rpl4p
50S ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.488
pyk
Pyruvate kinase; PK; Belongs to the pyruvate kinase family.
  
 
 0.488
APE_1980.1
Competence-damage protein CinA homolog; Belongs to the CinA family.
  
    0.472
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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